Abstract: Field experiments were conducted at the Teaching and Research Farm of the Department of Crop Science, Adamawa State University, Mubi in 2007 and 2008 cropping seasons with the aim of assessing the effect of spacing and NPK fertilizer on the yield and yield components of okra (Abelmoschus esculentus L.). Treatments consisted of four spacing (60x30 cm, 90x30 cm, 60x60 cm and 75x45 cm) and four NPK rates (0, 100, 150 and 200 kg ha-1) in a split plot design with plant spacing allocated to main plots and fertilizer in sub plots. The treatments were replicated three times to give a total of forty eight sub plots. Parameter such as number of fruits per plant, length of fruit, fresh weight of fruits per hectare and dry weight of fruits per hectare were measured. Data collected were subjected to Analysis of Variance (ANOVA) as described by Gomez and Gomez and treatment means were separated using Duncans Multiple Range Test (DMRT). Results showed that yield and yield components such as number of fruits per plant and length of fruit were not significantly affected by spacing in 2007. However, significant difference was obtained at 52 DAS in 2008. Number of fruits per plant and length of fruits were significantly affected by fertilizer levels. In 2008, there was significant interaction in respect to fresh weight of fruits per hectare. Also, there was significant interaction between spacing and fertilizer in respect to dry weight of fruits per hectare in 2007 and 2008. The results indicated that spacing of 90x30 cm and application of 150 kg ha-1 (22.5 kgN, 22.5 kg P2O5 and 22.5 kg K2O5) of NPK gave the highest yield of okra in Mubi.