Abstract: In recent years the use of probiotic bacteria in aquaculture has tremendous scope and the study of the application of probiotics in aquaculture has a glorious future. In the present study the probiotics, Silver-Ps was applied in culture ponds of Penaus monodon and was compared with control ponds (without probiotics). The salinity, pH, dissolved oxygen and temperature did not show significant difference between control and probiotics treated ponds. Average body weight, total production and survival rate of the ponds applied with probiotics were higher than that of control ponds. However feed conversion ratio was lower for the probiotics treated ponds than the control ponds. The shrimps in control ponds were seriously affected by bacterial infection; gill soaking and tail rot diseases. However, those problems are not encountered in probiotics applied ponds. The general conclusion obtained from the present study is that the probiotics plays a vital role in growth, survival and production of the shrimps by maintaining good water quality parameters through out the culture period.