Abstract: Background and Objectives: The search for cheap-safe tools for promoting farm animal productivity is the main concern of the animal nutritionists’ nowadays. The main objective of this study was to evaluate impact of cellulase new formula for promoting performance of lactating Baladi goats. Materials and Methods: Eighteen early lactating Baladi goats were randomly divided into 3 groups; the 1st group was fed control ration (50% concentrate feed mixture (CFM), 25% berseem (clover) hay and 25% wheat straw), the 2nd fed control ration+LAB produced cellulase at 42.16 IU kg–1 DM (R1), while the 3rd fed control ration+42.16 IU kg–1 DM of Pan-Zyme® (R2). The goats were fed dry matter according to 4% of their body weight for 9 weeks. Results: Goats fed cellulases supplemented rations (R1 and R2) showed higher (p<0.05) nutrients digestibility coefficients, milk yield and milk fat, protein, lactose and total solids yields than those of control. Cellulases supplementation did not cause any change in all of blood parameters (ex; glucose, protein AST, ALT and urea concentrations), milk fatty acids and amino acids profiles. Conclusion: Inclusion of the produced cellulase in lactating goat’s rations improved their ability for feed utilization and milk production with no bad effects on liver and kidney functions, which reflecting the safety and efficacy of the new cellulase product.