Abstract: A study has been conducted to evaluate the total flavonoids and phenolics contents of ten genotypes of Phaseolus vulgaris Linnaeus seeds as these compounds are natural antioxidants, disease preventing, anti-ageing and health promoting. All genotypes were distinct in shape, size and colour and their total flavonoids and phenolics contents also varied significantly. Genotype Triloki (K-198) contained the highest (1.67±0.00 quercetin equivalents) and Him-1 contained the lowest (0.29±0.01 mg g-1 quercetin equivalents) amount of total flavonoids. In case of total phenolics, genotype Him-1 had the highest (2.48±0.02 mg g-1 gallic acid equivalents) and PLB 14-1 had the lowest (0.66±0.02 mg g-1 gallic acid equivalents) amount of total phenolics contents. Analysis of variance (ANOVA) and Duncan’s Multiple Range Test (DMRT) also indicated the significant differences between total flavonoids and phenolics contents of all genotypes. The study therefore, revealed that consumption of a particular genotype of P. vulgaris seeds can promote the health and demote the ageing by its disease preventing potential of some natural antioxidants compounds present in cotyledons.