Zahida Tasawar
Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
Zeshan Siraj
Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
Nisar Ahmad
Ch. Pervaiz Elahi Institute of Cardiology, Multan, Pakistan
Mushtaq H. Lashari
Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
ABSTRACT
The present study has been carried out to determine the effects of Nigella saitva on the lipid profile in cardiac patients visited at Ch. Pervaiz Elahi Institute of Cardiology, Multan. The age of the subjects was 26-69 years. The eighty subjects were divided into two groups (interventional and non-interventional) through random stratification (n = 40/group) by weight. The interventional group given Nigella sativa and statin, non-interventional group given statin daily. Both groups were advised to take the recomended doses regularly for a period of six months and the patients were on usual care. Fasting blood samples were taken before and after two and six months treatment. In interventional group, cholesterol decreased by (-14.58%), LDL (-23.00%), VLDL (-15.16%) and triglycerides (-15.16%) significantly (p<0.05) after the treatment, whereas there was significant increase (p<0.05) in HDL cholesterol (3.18%) after six months. In non-interventional group the cholesterol decreased by (+1.17%), LDL (-4.13%), VLDL (-3.10%) and triglycerides (-2.12%) non significantly (p>0.05) after the treatment, whereas there was significant increase (p<0.05) in HDL (+5.87) after six months. In conclusion, the Nigella sativa is effective to change the lipid profile significantly in a way which is beneficial to heart.
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How to cite this article
Zahida Tasawar, Zeshan Siraj, Nisar Ahmad and Mushtaq H. Lashari, 2011. The Effects of Nigella sativa (Kalonji) on Lipid Profile in Patients with Stable Coronary Artery Disease in Multan, Pakistan. Pakistan Journal of Nutrition, 10: 162-167.
DOI: 10.3923/pjn.2011.162.167
URL: https://scialert.net/abstract/?doi=pjn.2011.162.167
DOI: 10.3923/pjn.2011.162.167
URL: https://scialert.net/abstract/?doi=pjn.2011.162.167
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Tahira khan Reply
this paper is very informative for the coronary heart disease and the black cumin remedy