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Pakistan Journal of Nutrition

Year: 2011 | Volume: 10 | Issue: 2 | Page No.: 162-167
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Authors

Zahida Tasawar

Zeshan Siraj

Nisar Ahmad

Mushtaq H. Lashari

Keywords

Research Article

The Effects of Nigella sativa (Kalonji) on Lipid Profile in Patients with Stable Coronary Artery Disease in Multan, Pakistan

Zahida Tasawar, Zeshan Siraj, Nisar Ahmad and Mushtaq H. Lashari
The present study has been carried out to determine the effects of Nigella saitva on the lipid profile in cardiac patients visited at Ch. Pervaiz Elahi Institute of Cardiology, Multan. The age of the subjects was 26-69 years. The eighty subjects were divided into two groups (interventional and non-interventional) through random stratification (n = 40/group) by weight. The interventional group given Nigella sativa and statin, non-interventional group given statin daily. Both groups were advised to take the recomended doses regularly for a period of six months and the patients were on usual care. Fasting blood samples were taken before and after two and six month’s treatment. In interventional group, cholesterol decreased by (-14.58%), LDL (-23.00%), VLDL (-15.16%) and triglycerides (-15.16%) significantly (p<0.05) after the treatment, whereas there was significant increase (p<0.05) in HDL cholesterol (3.18%) after six months. In non-interventional group the cholesterol decreased by (+1.17%), LDL (-4.13%), VLDL (-3.10%) and triglycerides (-2.12%) non significantly (p>0.05) after the treatment, whereas there was significant increase (p<0.05) in HDL (+5.87) after six months. In conclusion, the Nigella sativa is effective to change the lipid profile significantly in a way which is beneficial to heart.
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Tahira khan Reply

this paper is very informative for the coronary heart disease and the black cumin remedy

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