In order to valorise the pharmaceutical potential of
natural products, 10 plants of nine different families collected on ethnobotanic
informations around Yaoundé in Cameroon were extracted. Seventeen
organic and hydro-organic extracts were tested for their biological effects.
The in vitro evaluation of antibacterial and antifungal activity
was carried out by the well agar diffusion method on seven Gram positive
and Gram negative bacteria (P. aeruginosa, E. coli, S.
faecalis,S. choelera, P. mirabilis and M. morganii)
and two groups of fungi (Filamentous, Yeast). The results showed that
12 of the 17 extracts demonstrated antibacterial activity against the
seven pathogenic bacteria tested. The growth inhibition halos were ranged
from 8.00 to 32.33. Among them, extracts of Solanum aculeastrum
(Solanaceae) and Syzygium guinensis (Myrtaceae) showed the higher
antibacterial activity. For the antifungal activity, growth inhibition
halos varied from 8.00 to 17.55 mostly against Geotrichum candidum
and Penicillium species. The extracts S. aculeastrum
demonstrated antibacterial and antifungal activity.