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Journal of Biological Sciences

Year: 2008 | Volume: 8 | Issue: 5 | Page No.: 902-907
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Authors

C.A. Pieme

J.P. Dzoyem

F.A. Kechia

F.X. Etoa

V. Penlap

Keywords

Research Article

In vitro Antimicrobial Activity of Extracts from Some Cameroonian Medicinal Plants

C.A. Pieme, J.P. Dzoyem, F.A. Kechia, F.X. Etoa and V. Penlap
In order to valorise the pharmaceutical potential of natural products, 10 plants of nine different families collected on ethnobotanic informations around Yaoundé in Cameroon were extracted. Seventeen organic and hydro-organic extracts were tested for their biological effects. The in vitro evaluation of antibacterial and antifungal activity was carried out by the well agar diffusion method on seven Gram positive and Gram negative bacteria (P. aeruginosa, E. coli, S. faecalis,S. choelera, P. mirabilis and M. morganii) and two groups of fungi (Filamentous, Yeast). The results showed that 12 of the 17 extracts demonstrated antibacterial activity against the seven pathogenic bacteria tested. The growth inhibition halos were ranged from 8.00 to 32.33. Among them, extracts of Solanum aculeastrum (Solanaceae) and Syzygium guinensis (Myrtaceae) showed the higher antibacterial activity. For the antifungal activity, growth inhibition halos varied from 8.00 to 17.55 mostly against Geotrichum candidum and Penicillium species. The extracts S. aculeastrum demonstrated antibacterial and antifungal activity.
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