Ayida Al-Wahaibi
Department of Human and Clinical Anatomy, College of Medicine and Health Sciences, Sultan Qaboos University, P.O.Box 35, Alkhodh 123, Sultanate of Oman
W.M. Wan Nazaimoon
Diabetes and Endocrine Unit, Institute for Medical Research (IMR), Jalan pahang, 50588 Kuala Lumpur, Malaysia
W.N. Norsyam
Department of Anatomy, Faculty of Medicine, University Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
H.S. Farihah
Department of Anatomy, Faculty of Medicine, University Kebangsaan Malaysia (UKM),
Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
A.L. Azian
Department of Anatomy, Faculty of Medicine, University Kebangsaan Malaysia (UKM),
Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
ABSTRACT
Labisia pumila var alata, locally known Kacip Fatimah, is a traditional herb used by Malay women to induce and facilitate childbirth as well as to increase a woman's libido. This study was aimed to investigate the effect of Labisia pumila consumption on maintaining the integrity of the aortic wall in ovariectomized rats. Thirty-five adult female Sprague Dawley rats, 6 months old, were used in the experiment. Rats were divided into Normal (NOR) and ovariectomized (OVXC, KF and ERT) groups. Body weight was checked and recorded monthly. After four months, rats were sacrificed by cervical dislocation and tissue samples from the aorta were collected for histological studies. Results showed that water extract of Labisia pumila-treatment maintained the elastic lamellae architecture of the ovariectomized rat aortae in a manner comparable to that of the normal rats. Results implied a possible role for Labisia pumila in modulating postmenopausal cardiovascular risks.
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How to cite this article
Ayida Al-Wahaibi, W.M. Wan Nazaimoon, W.N. Norsyam, H.S. Farihah and A.L. Azian, 2008. Effect of Water Extract of Labisia pumila Var
Alata on Aorta of Ovariectomized Sprague Dawley Rats. Pakistan Journal of Nutrition, 7: 208-213.
DOI: 10.3923/pjn.2008.208.213
URL: https://scialert.net/abstract/?doi=pjn.2008.208.213
DOI: 10.3923/pjn.2008.208.213
URL: https://scialert.net/abstract/?doi=pjn.2008.208.213