J.M. Malekzadeh
Department of Nutrition and Biochemistry,
School of Health,
Tehran University of Medical Sciences,
Tehran, Iran
S.A. Keshavarz
Department of Nutrition and Biochemistry,
School of Health,
Tehran University of Medical Sciences,
Tehran, Iran
F. Siassi
Department of Nutrition and Biochemistry,
School of Health,
Tehran University of Medical Sciences,
Tehran, Iran
M. Eshraghian
Department of Epidemiology and Statistics, School of Health, Tehran University of Medical Sciences, Tehran, Iran
M. Kadkhodaee
Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
A.R. Dorosty
Department of Nutrition and Biochemistry,
School of Health,
Tehran University of Medical Sciences,
Tehran, Iran
A. Aliehpour
Shariaati Hospital of Tehran, Tehran University of Medical Sciences, Tehran, Iran
M. Chamari
Department of Nutrition and Biochemistry,
School of Health,
Tehran University of Medical Sciences,
Tehran, Iran
ABSTRACT
Recently, studies have focused on the effects of dietary calcium on the weight and fatness. Some of these studies have indicated that there is negative relationship between dietary calcium and body fat, while others have reported no such effects. There are also controversies over serum parathyroid hormone, as its mechanism, on body fat and weight. The objective of the present study was to evaluate the effects of three dietary calcium levels (0.2%, 0.5% or 1.2% Ca2+) on body fat and weight gain in male Sprague-Dawley rats, using same diet composition for nutrients other than calcium. The study duration was 72 days. At the end, truncal blood samples were drawn from decapitated rats to measure the effects of diets on serum calcium, PTH and vitamin D. The carcasses were minced and homogenized to measure their body fat percent by the methods of Soxhelet. There were no significant effects of dietary calcium on food intake (p>0.05), body weight gain (p>0.05) or carcass fat content (p>0.05), while the serum PTH levels were inversely related to calcium intake (p<0.05). In conclusion, our findings do not support the effects of dietary calcium and parathyroid hormone on body fat and weight.
PDF Citation
How to cite this article
J.M. Malekzadeh, S.A. Keshavarz, F. Siassi, M. Eshraghian, M. Kadkhodaee, A.R. Dorosty, A. Aliehpour and M. Chamari, 2007. Dietary Calcium Had No Reducing Effect on Body Fat and Weight Gain in Sprague-Dawley Rats. Pakistan Journal of Nutrition, 6: 478-484.
DOI: 10.3923/pjn.2007.478.484
URL: https://scialert.net/abstract/?doi=pjn.2007.478.484
DOI: 10.3923/pjn.2007.478.484
URL: https://scialert.net/abstract/?doi=pjn.2007.478.484