Zakia Sultana Sathi
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
Md. Aziz Abdur Rahman
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
M. A. Gafur
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
ABSTRACT
A pure antimicrobial compound was isolated from the chloroform extract of the broth culture of Streptomyces species by preparative thin layer chromatography (PTLC) and was characterized as 4-hydroxy nitrobenzene (ZS-3) on the basis of spectral data (UV, IR, 1H-NMR, HMBC and HMQC). The compound showed significant antimicrobial activity against six gram positive bacteria, ten gram negative bacteria and three pathogenic fungi. The minimum inhibitory concentration (MIC) of the compound determined against ten pathogenic organisms was found to be between 32-64 g/ml.
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How to cite this article
Zakia Sultana Sathi, Md. Aziz Abdur Rahman and M. A. Gafur, 2001. Identification and In vitro Antimicrobial Activity of a Compound Isolated from Streptomyces Species. Pakistan Journal of Biological Sciences, 4: 1523-1525.
DOI: 10.3923/pjbs.2001.1523.1525
URL: https://scialert.net/abstract/?doi=pjbs.2001.1523.1525
DOI: 10.3923/pjbs.2001.1523.1525
URL: https://scialert.net/abstract/?doi=pjbs.2001.1523.1525
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