Research Article
Effect of Allium cepa (Onion) Extract on Cadmium-induced Nephrotoxicity in Rats
Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
R.E. Akhigbe
Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
A.A. Adewale
Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
J.A. Badmus
Department of Biochemistry, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
S.B. Olaleye
Department of Physiology, College of Medicine, University of Ibadan, Ibadan, Oyo Atate, Nigeria
F.O. Ajao
Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
W.A. Saka
Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
O.Q. Owolabi
Department of Biochemistry, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
ruchi singh thakur Reply
how we can find Changes in body and kidney weights were determined. Renal weight index, 24 h urine volume, renal clearance and lipid peroxidation status ?
AKHIGBE, Roland Eghoghosoa
1.Changes in body weight was determined by daily measurement of body weight, then deduct the initial body weight from the final body weight
2. Kidney weight was determined and not the change in kidney weight. This was done by excising the kidney and weighing using a micro-weighing device
3. Renal weight index=kidney weight/body weight
4. 24-h urine volume = total urine volume in a day
5. renal clearanc is the normal physiology renal clearence
6. lipid peroxidation status was determined by assay of MDA(lipid peroxidation index)and SOD(antioxidant)in plasma and tissue.
The detail of all these are in the body of the manuscript
venu gopal Reply
how u are prepared the allium cepa extration??????????????????
AKHIGBE, Roland E
The extraction of Allium cepa was explained in detail in the Materials and Methods section of the manuscript.
Please, refer to the full manuscript for better understanding.
Thanks
Oyewole Rasheed Adedamola Reply
Nice work.............. so interesting....... Thumbs up to the great scientist and to my supervisor Mrs. S.F IGE , you are the best