Shahmim Akhter
Department of Human Nutrition
NWFP, Agricultural University;
Peshawar, Pakistan
Alam Khan
Department of Human Nutrition
NWFP, Agricultural University;
Peshawar, Pakistan
Mohammad Mohsin Siddiqui
Department of Animal Husbandry,
NWFP, Agricultural University, Peshawar, Pakistan
Gul Nawab
Department of Human Nutrition, NWFP, Agricultural University, Peshawar, Pakistan
ABSTRACT
Frequencies of thyroid problems in different age, sex and seasons were determined from the relative concentration of thyroid hormones (T3 and T4) and thyroid stimulating hormone (TSH) in 9054 patients. These patients visited the radioimmunoassay (RIA) laboratory of the Institute of Radiotherapy and Nuclear Medicine (IRNUM) Peshawar during the years 1984-1990 (except 1987) and 1995 and 1996. The patients were classified into infants, children, adults and old age groups according to their age, into males and females according to their sex and into winter, spring, summer and autumn according to their visit to the laboratory. T3 and T4 in the blood serum of these patients were determined by radioimmunoassay (RIA) and their TSH in the blood serum were determined by immuno-radiometric assay (IRMA). The data revealed that 54% thyroid patients were having normal levels of T3, T4 and TSH. Considering all age groups together, the frequencies of hyperthyroidism/Thyrotoxicosis and hypothyroidism were 5.1 and 4.0% respectively. Similarly, the frequencies of subclinical hyperthyroidism and subclinical hypothyroidism were 5.8 and 5.4% respectively. The frequencies of other thyroid problems were 25.8%. The frequency of hyperthyroidism/ thyrotoxicosis was higher in adults group (2.9%) followed by old age group (2.0%), children group (0.2%) and infants group (0.01%). Similarly the frequency of hypothyroidism was higher in adults group followed by old age group, children group and infants group were 1.8, 1.3, 0.7, 0.1% respectively. Similar pattern of frequencies of subclinical hyperthyroidism, subclinical hypothyroidism and other thyroid problems was observed. Iodized salted should be used only in iodine deficient areas and with caution.
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How to cite this article
Shahmim Akhter, Alam Khan, Mohammad Mohsin Siddiqui and Gul Nawab, 2001. Frequencies of Thyroid Problems in Different Age, Sex and Seasons. Journal of Medical Sciences, 1: 153-156.
DOI: 10.3923/jms.2001.153.156
URL: https://scialert.net/abstract/?doi=jms.2001.153.156
DOI: 10.3923/jms.2001.153.156
URL: https://scialert.net/abstract/?doi=jms.2001.153.156
REFERENCES
- Connolly, R.J., 1971. An increase in thyrotoxicosis in Southern Tasmania after an increase in dietary iodine. Med. J. Aust., 2: 1268-1271.
PubMedDirect Link - Connolly, R.J., 1973. The changing age incidence of jodbasedow in Tasmania. Med. J. Aust., 2: 171-174.
PubMedDirect Link - Gadde, K.M. and R.R. Krishnan, 1994. Endocrine factors in depression. Psychiat. Ann., 24: 521-524.
CrossRefDirect Link - Galofre, J.C., L. Fernandez-Calvet, M. Rios and R.V.G. Garcia-Mayor, 1994. Increased incidence of thyrotoxicosis after iodine supplementation in an iodine sufficient area. J. Endocrinol. Invest., 17: 23-27.
CrossRefDirect Link - Haggerty, Jr.J.J. and A.J. Prange Jr., 1995. Borderline hypothyroidism and depression. Ann. Rev. Med., 46: 37-46.
CrossRefDirect Link - Stewart, J.C., G.I. Vidor, I.H. Buttfield and B.S. Hetzel, 1971. Epidemic thyrotoxicosis in Northern Tasmania: Studies of clinical features and iodine nutrition. Aust. N. Z. J. Med., 1: 203-211.
CrossRefPubMedDirect Link - Vidor, G.I., J.C. Stewart, J.R. Wall, A. Wangel and B.S. Hetzel, 1973. Pathogenesis of iodine-induced thyrotoxicosis: Studies in Northern Tasmania. J. Clin. Endocrinol. Metab., 37: 901-909.
CrossRefPubMedDirect Link