Sayed Alam
Department of Biology, Faculty of Science and Environmental Studies, Universiti Putra Malaysia,
43400 UPM, Serdang, Selangor, Malaysia
M. A. Jalil Miah
Department of Biology, Faculty of Science and Environmental Studies, Universiti Putra Malaysia,
43400 UPM, Serdang, Selangor, Malaysia
Azizul Islam
Department of Biology, Faculty of Science and Environmental Studies, Universiti Putra Malaysia,
43400 UPM, Serdang, Selangor, Malaysia
ABSTRACT
In the present study 8-γ,γ-dimethyallyl-5, 7-dimethoxyflavone [ovaliflavone, 6] has been synthesized from phloroacetophenone via chalcone precursor and by its treatment with DMSO/I2 or diphenyl sulphide. The antibacterial and antifungal activities of ovaliflavone and its corresponding chalcone were found in vitro by the filter paper disc diffusion method and poisoned food technique, respectively. Compound 6 showed good antibacterial and antifungal activities to the some selected bacterial and fungal strain.
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How to cite this article
Sayed Alam, M. A. Jalil Miah and Azizul Islam, 2004. In vitro Studies of Antimicrobial Activity of Synthetic
Ovaliflavone. Journal of Biological Sciences, 4: 527-531.
DOI: 10.3923/jbs.2004.527.531
URL: https://scialert.net/abstract/?doi=jbs.2004.527.531
DOI: 10.3923/jbs.2004.527.531
URL: https://scialert.net/abstract/?doi=jbs.2004.527.531
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