P. Krishnamoorthy
Postgraduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-6001 13, Tamilnadu, India
S. Vairamuthu
Department of Veterinary Pathology, Madras Veterinary College, Chennai�600 007, Tamilnadu, India Dr. Al-M.
C. Balachandran
Centralised Clinical Laboratory, Madras Veterinary College, Chennai 600007, Tamilnadu, India
B. Muralimanohar
Department of Veterinary Pathology, Madras Veterinary College, Chennai�600 007, Tamilnadu, India Dr. Al-M.
ABSTRACT
The present work was undertaken to study the haematobiochemical changes in chlorpyriphos and T-2 toxin fed broiler chicken. Known amounts of chlorpyriphos and T-2 toxin containing powdered wheat substrates were incorporated into the toxin free broiler starter mash, singly and in combination to yield 45 ppm chlorpyriphos and 0.5 ppm T-2 toxin. Forty eight day-old broiler chicks were randomly allotted into four groups of 12 each i.e., control, chlorpyriphos, T-2 and chlorpyriphos+T-2 groups and fed with toxin mixed diets from 0 to 4 weeks of age and studied various haematobiochemical parameters on 14th and 28th day of age. PCV and Hb levels decreased significantly (P< 0.01) in toxin fed birds indicating anaemia. Serum total protein, albumin, globulin and albumin/globulin ratio decreased significantly (P< 0.01) in T-2 fed group. Serum glucose and cholesterol values decreased significantly (P< 0.01) in chlorpyriphos group. AST, ALT and ALP values increased significantly (P< 0.01) in T-2 and chlorpyriphos+T-2 groups. Chlorpyriphos fed birds showed increased ALT. Chlorpyriphos and chlorpyriphos+T-2 fed groups showed significant (P< 0.01) increase in serum amylase values. Decreased serum lipase values were observed in T-2 and chlorpyriphos+T-2 groups. No significant differences were observed in values of blood urea nitrogen, creatinine, uric acid and GGT between the control and toxin treated groups. Chlorpyriphos and T-2 toxins affected functions of various organs in broiler chicken, the effect being less than additive.
How to cite this article
P. Krishnamoorthy, S. Vairamuthu, C. Balachandran and B. Muralimanohar, 2006. Chlorpyriphos and T-2 Toxin Induced Haemato-Biochemical
Alterations in Broiler Chicken. International Journal of Poultry Science, 5: 173-177.
DOI: 10.3923/ijps.2006.173.177
URL: https://scialert.net/abstract/?doi=ijps.2006.173.177
DOI: 10.3923/ijps.2006.173.177
URL: https://scialert.net/abstract/?doi=ijps.2006.173.177