M.B. Rahman
Not Available
M.M. Rahman
Not Available
M. Rahman
Not Available
S.M.L. Kabir
Not Available
K.H.M.N.H. Nazir
Not Available
M.M. Amin
Not Available
ABSTRACT
Thirty day-old chicks of Cobb-100 breed with the history of vaccination of parent stock against Newcastle disease (ND) were equally divided into two groups such as group A and B. At 7 days of age of birds, group A was vaccinated with experimentally prepared V4HR-ND vaccine via eye drop @ 106.0EID50/bird to determine the efficacy of this vaccine while group B was kept as unvaccinated control. The birds were used for the study during the period from October 2003 to December 2003. Each bird of group A was boostered with same vaccine @ same dose at 24 days of age. Both the groups (A and B) were challenged after two weeks of post-booster vaccination with 0.25ml inoculum containing 105.0EID50 of virulent field isolates of ND virus intramuscularly. The results of challenge experiment revealed that six birds (40%) of group A succumbed within 3 to 4 days of post-challenge, whereas 15 (100%) unvaccinated control birds of group B showed clinical illness and ultimately died within 3 to 5 days. Thus, the experimental V4HR-ND vaccine conferred 60% protection of vaccinated birds against challenge infection. The mean values of Haemagglutination inhibition (HI) antibody titres of birds in group A were found to have significantly (P<0.01) increased at two weeks of post-booster vaccination. These results indicated that experimental V4HR-ND vaccine induced sufficient humoral immune response which gives satisfactory level of protection against ND.
PDF Citation
How to cite this article
M.B. Rahman, M.M. Rahman, M. Rahman, S.M.L. Kabir, K.H.M.N.H. Nazir and M.M. Amin, 2004. Efficacy of V4HR Newcastle Disease
(V4HR-ND) Vaccine in Broiler Birds in Bangladesh. International Journal of Poultry Science, 3: 365-368.
DOI: 10.3923/ijps.2004.365.368
URL: https://scialert.net/abstract/?doi=ijps.2004.365.368
DOI: 10.3923/ijps.2004.365.368
URL: https://scialert.net/abstract/?doi=ijps.2004.365.368