Trends in Medical Research1819-35872151-6065Science International10.3923/tmr.2017.32.44IssaReem A. BashetiIman A. 12017121Objectives: To assess the current use of herbal products among chronically ill patients in Jordan and to review the impact of the used herbal products on their treatments safety and efficiency. Materials and Methods: This study was a questionnaire based cross-sectional study conducted between March and June, 2016. The developed and validated questionnaire consisted of 2 different forms, one for patients with chronic diseases and one for the community pharmacists. Patients and pharmacists were randomly recruited into this study by pharmacy students skilled to perform the data collection. Results: About 376 patients were recruited into this study (mean age 43 years, 54% female). About 216 (57.4%) were using 43 different herbal products. The most common chronic diseases suffered by the patients were hypertension, diabetes and hyperlipidemia. Males and older patients were more likely to experience unsafe or inefficient use of herbal products. Only 54.2% of the patients informed their pharmacists of their use of herbal products. A minority of the pharmacists (8.2%) reported very good knowledge of herbal products use and herbs-drugs interactions and only (11.3%) always ask their patients about their use of any herbal products. Conclusion: Many chronically ill patients in Jordan use herbal products for the management of their chronic conditions. Inefficient use is common mainly amongst males. Patients and pharmacists are not communicating as needed regarding patients use of herbal products. New strategies need to be implemented in the country to resolve these vital issues.]]>Arzu, Y. and T. Thiagarajan,201641520Micozzi, M.S.,20145th Edn.,Pages: 720Pages: 720Benzie, I.F.F. and S. Wachtel-Galor,20112nd Edn.,Pages: 499Pages: 499Tulunay, M., C. Aypak, H. Yikilkan and S. Gorpelioglu,20154217220Gyasi, R.M., F. Asante, K. Abass, J.Y. Yeboah, S. Adu-Gyamfi and P.A. Amoah,20162016De Souza Silva, J.E., C.A.S. Souza, T.B. da Silva, I.A. Gomes and G. de Carvalho Brito et al.,201459227233Al-Ramah, R., N. Jaradat, R. Shalalfeh, S. Nasir, Y. Manasra, I. Shalalfeh and Y. Esam,20152015Khdour, M.R., M. Kurdi, H.O. Hallak, A.S. Jarab, M. Dweib and Q.N. Al-Shahed,20162016Pitkala, K.H., M.H. Suominen, J.S. Bell and T.E. Strandberg,201648586602James, P.B. and A.J. Bah,20142014Pelkonen, O., Q. Xu and T.P. Fan,2014417Abu-Irmaileh, B.E. and F.U. Afifi,200389193197Aburjai, T., M. Hudaib, R. Tayyem, M. Yousef and M. Qishawi,2007110294304Saad, B., H. Azaizeh, G. Abu-Hijleh and S. Said,20063433439Ekor, M.,20142014Brantley, S.J., A.A. Argikar, Y.S. Lin, S. Nagar and M.F. Paine,201442301317Braun, L. and M. Cohen,2015Vol. 2, 4th Edn.,Pages: 1384Pages: 1384Mukherjee, P.K.,2015Pages: 556Pages: 556Alissa, E.M.,201436413422Qunaibi, E., I.A. Basheti, S.A. Hamadi, N.R. Bulatova, A. Shanah and E. Abu-Gharbieh,201312247253Ali-Shtayeh, M.S., R.M. Jamous and R.M. Jamous,2012181621Herrera-Arellano, A., S. Flores-Romero, M.A. Chavez-Soto and J. Tortorie-Ilo,2004Hibiscus sabdariffa in patients with mild to moderate hypertension: A controlled and randomized clinical trial.]]>5375382Herrera-Arellano, A., J. Miranda-Sanchez, P. Avila-Castro, S. Herrera-Alvarez and J.E. Jimenez-Ferrer et al.,2007Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial.]]>73612Singh, R.B., A.M. Niaz, J.P. Sharma, R. Kumar, V. Rastogi and M. Moshiri,199711485491Singh, R.B., G. Dubnov, M.A. Niaz, S. Ghosh and R. Singh et al.,200236014551461Popping, S., H. Rose, I. Ionescu, Y. Fischer and H. Kammermeier,19954511571161Uchida, S., N. Ikari, H. Ohta, M. Niwa, G. Nonaka, I. Nishioka and M. Ozaki,198743242246Silagy, C.A. and H.A. Neil,199412463468Bairati, I., L. Roy and F. Meyer,199284146Prisco, D., R. Paniccia, B. Bandinelli, M. Filippini and I. Francalanci et al.,199891105112Salvig, J.D., S.F. Olsen and N.J. Secher,1996103529533Kook, S., G.H. Kim and K. Choi,200912552560Bloedon, L.T. and P.O. Szapary,2004621827Khayyal, M.T., M.A. El-Ghazaly, D.M. Abdallah, N.N. Nassar, S.N. Okpanyi and M.H. Kreuter,2002Olea europaed) in L-NAME induced hypertension in rats.]]>52797802Ames, N. and C. Rhymer,20081381237S1243SSultan, K., M. Zakir, H. Khan, A. Rauf, N.U. Akber and M.A. Khan,2016Eruca sativa Miller (rocket salad) hydroalcoholic extract.]]>3012021204Roman-Ramos, R., J.L. Flores-Saenz and F.J. Alarcon-Aguilar,1995482532Sheela, C.G., K. Kumud and K.T. Augusti,199561356357Al-Azzawie, H.F. and M.S. Alhamdani,20057813711377Gonzalez, M., A. Zarzuelo, M.J. Gamez, M.P. Utrilla, J. Jimenez and I. Osuna,199258513515Leung, L, R. Birtwhistle, J. Kotecha, S. Hannah and S. Cuthbertson,2009Momordica charantia (bitter melon): A mini review.]]>10217031708Ooi, C.P., Z. Yassin and T.A. Hamid,20102010Tomoda, M., N. Shimizu, R. Gonda, M. Kanari, H. Yamada and H. Hikino,1989190323328Sabitha, V., S. Ramachandran, K.R. Naveen and K. Panneerselvam,2012in vivo antioxidant property of Abelmoschus esculentus (L) Moench. fruit seed and peel powders in streptozotocin-induced diabetic rats.]]>3188193Sabitha, V., S. Ramachandran, K.R. Naveen and K. Panneerselvam,2011Abelmoschus esculentus (L.) Moench. in streptozotocin-induced diabetic rats.]]>3397402Chambers, B.K. and M.E. Camire,20032626952696Kadnur, S.V. and R.K. Goyal,2005Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats.]]>4311611164Sekiya, K., A. Ohtani and S. Kusano,200422153156Bolkent, S., R. Yanardag, O. Ozsoy-Sacan and O. Karabulut-Bulan,2004Petroselinum crispum) on the liver of diabetic rats: A morphological and biochemical study.]]>18996999Ozsoy-Sacan, O., R. Yanardag, H. Orak, Y. Ozgey, A. Yarat and T. Tunali,2006Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats.]]>104175181Yanardag, R., S. Bolkent, A. Tabakoglu-Oguz and O. Ozsoy-Sacan,2003Petroselinum crispum extract on pancreatic B cells and blood glucose of streptozotocin-induced diabetic rats.]]>2612061210Anderson, R.A., C.L. Broadhurst, M.M. Polansky, W.F. Schmidt and A. Khan et al.,2004526570Baker, W.L., G. Gutierrez-Williams, C.M. White, J. Kluger and C.I. Coleman,2008314143Blevins, S.M., M.J. Leyva, J. Brown, J. Wright, R.H. Scofield and C.E. Aston,20073022362237Qin, B., M. Nagasaki, M. Ren, G. Bajotto, Y. Oshida and Y. Sato,2003in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats.]]>62139148Eidi, M., A. Eidi and H. Zamanizadeh,2005Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats.]]>100310313Lima, C.F., M.F. Azevedo, R. Araujo, M. Fernandes-Ferreira and C. Pereira-Wilson,2006Salvia officinalis (common sage): Is it useful in diabetes prevention?]]>96326333Srivastava, J.K., E. Shankar and S. Gupta,20103895901Kawabata, J., K. Mizuhata, E. Sato, T. Nishioka, Y. Aoyama and T. Kasai,2003Origanum majorana) leaves.]]>67445447Chudnovskiy, R., A. Thompson, K. Tharp, M. Hellerstein, J.L. Napoli and A. Stahl,20142014Holman, R.R.,201396768Frank, J., T.W. Gerge, J.K. Lodge, A.M. Rodriguez-Mateos, J.P.E. Spencer, A.M. Minihane and G. Rimbach,20091395862Hsu, C.H., T.H. Tsai, Y.H. Kao, K.C. Hwang, T.Y. Tseng and P. Chou,200827363370Maki, K.C., M.S. Reeves, M. Farmer, K. Yasunaga and N. Matsuo et al.,2009139264270Nantz, M.P., C.A. Rowe, J.F. Bukowski and S.S. Percival,2009Camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study.]]>25147154Vafa, M.R., F. Mohammadi, F. Shidfar, M.S. Sormaghi, I. Heidari, B. Golestan and F. Amiri,20123531536He, K.,20095295114Al-Jamal, A.R. and A. Taha,2011Rosmarinus officinalis) on lipid profile of diabetic rats.]]>4199204Bordia, T., N. Mohammed, M. Thomson and M. Ali,199654183186Chen, J.H., H.I. Chen, S.J. Tsai and C.J. Jen,20001303437Kumari, K., B.C. Mathew and K.T. Augusti,1995Allium cepa Linn.]]>324954Gardner, C.D., L.D. Lawson, E. Block, L.M. Chatterjee, A. Kiazand, R.R. Balise and H.C. Kremer,2007167346353Superko, H.R. and R.M. Krauss,200035321326Englisch, W., C. Beckers, M. Unkauf, M. Ruepp and V. Zinserling,200050260265Bjorkman, M., I. Klingen, A.N.E. Birch, A.M. Bones and T.J.A. Bruce et al.,201172538556Traka, M.H. and R.F. Mithen,20112324832497Neelakantan, N., M. Narayanan, R.J. de Souza and R.M. van Dam,2014Trigonella foenum-graecum L.) intake on glycemia: A meta-analysis of clinical trials.]]>2014Deni, B.,2001Singh, O., Z. Khanam, N. Misra and M.K. Srivastava,2011Matricaria chamomilla L.): An overview.]]>58295Gurrola-Diaz, C.M., P.M. Garcia-Lopez, S. Sanchez-Enriquez, R. Troyo-Sanroman, I. Andrade-Gonzalez and J.F. Gomez-Leyva,2010Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy).]]>17500505Hernandez-Perez, F. and A. Herrera-Arellano,2011Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trial].]]>49469480, (In Spanish)Kuriyan, R., D.R. Kumar, R. Rajendran and A.V. Kurpad,2010Hibiscus sabdariffa leaves in hyperlipidemic Indians: A double blind, placebo controlled trial.]]>2010