Research Journal of Phytochemistry1819-34712151-6081Science International10.3923/rjphyto.2017.35.41Melastoma malabathricum and Melastoma beccarianum Leaf Crude Extracts]]>DirisM.N. BasriA.M. MetaliF. AhmadN. TahaH. 12017111Background:Melastoma malabathricum is an important ethnomedicinal plant that has been rigorously studied for its medicinal properties, however, its closely related species, M. beccarianum has not been studied. Methodology: The phytochemical constituents of M. malabathricum and M. beccarianum were determined by gas chromatography mass spectrometry (GC/MS) analysis and their antimicrobial activities by agar-well diffusion method. Results: Similar chemical compositions were identified between the two Melastoma species, where three compounds were only detected in M. malabathricum methanol leaf crude extract, i.e., 8,11-octadecadienoic acid methyl ester, stearic acid methyl ester and tocopherol, whereas α-tocopherol-β-D-mannoside was only detected in M. beccarianum. The former was predominantly characterised by trans-squalene (17.02%) and the latter was by 5-hydroxymethylfurfural (15.76%). Both methanol extracts were found to exhibit antibacterial activities against Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. However, the extracts did not display antifungal activity against Saccharomyces cerevisiae under the conditions tested. Likewise, both aqueous leaf crude extracts did not show any detectable antibacterial activities. Conclusion: This study not only supported the close relatedness of M. malabathricum and M. beccarianum in terms of their phytochemical constituents and antimicrobial properties but also showed that these species were still uniquely different from each other.]]>Goldenberg, R. and G.J. Shepherd,1998Melastomataceae in cerrado vegetation.]]>2111329Joffry, S.M., N.J. Yob, M.S. Rofiee, M.M.R.M.M. Affandi and Z. Suhaili et al.,2012Melastoma malabathricum (L.) Smith ethnomedicinal uses, chemical constituents and pharmacological properties: A review.]]>2012Metali, F., A.S. Kamariah and D.S. Edwards,2005Melastomamalabathricum L.) in Brunei Darussalam.]]>2005pp: 399403Rajenderan, M.T.,2010Melastoma malabathricum.]]>33444Grasvenol, P.W., A. Supriono and D.O. Gray,19954597111Lohezic-Le-Devehat, F., A. Bakhtiar, C. Bezivin, M. Amoros and J. Boustie,200273400405Nazlina, I., S. Norha, A.W.N. Zarina and I.B. Ahmad,2008Melastoma malabathricum extracts.]]>375355Thatoi, H.N., S.K. Panda, S.K. Rath and S.K. Dutta,20087260267Mohamed, Z., N. Ibrahim and I. Ahmad,2008Melastoma malabathricum methanol extract.]]>37107113Wong, K.C., D.M. Hag Ali and P.L. Boey,2012Melastoma malabathricum L.]]>26609618Sulaiman, M.R., M.N. Somchit, D.A. Israf, Z. Ahmad and S. Moin,2004Melastoma malabathricum ethanolic extract in mice.]]>75667672Zakaria, Z.A., R.N.R.M. Nor, G.H. Kumar, Z.D.A. Ghani and M.R. Sulaiman et al.,2006Melastoma malabathricum leaves aqueous extract in experimental animals.]]>8412911299Hussain, F., M.A. Abdulla, S.M. Noor, S. Ismail and H.M. Ali,2008Melastoma malabathricum aqueous leaf extract against ethanol-induced gastric ulcer iin rats.]]>4438441Zakaria, Z.A., T. Balan, S.S. Mamat, N. Mohtarrudin, T.L. Kek and M.Z. Salleh,2015Melastoma malabathricum leaves. BMC Complement.]]>15135135Susanti, D., H.M. Sirat, F. Ahmad, R.M. Ali, N. Aimi and M. Kitajima,2007Melastoma malabathricum L.]]>103710716Yoshida, T., F. Nakata, K. Hosotani, A. Nitta and T. Okudat,1992Melastoma malabathricum.]]>3128292833Nuresti, S., S.H. Baek and A. Asari,2003Melastoma malabathricum.]]>162833Janna, O.A., A. Khairul, M. Maziah and Y. Mohd,2006Melastoma malabathricum.]]>5170174Susanti, D., H.M. Sirat, F. Ahmad and R.M. Ali,2008Melastoma malabathricum L.]]>518Abah, S.E. and L.O. Egwari,20113205209Trusheva, B., D. Trunkova, and V. Bankova,20072007Ncube, N.S., A.J. Afolayan and A.I. Okoh,2008717971806Raman, B.V., L.A. Samuel, M. Pardha Saradhi, B. Narashimha Rao, A.N. Vamsi Krishna, M. Sudhakar and T.M. Radhakrishnan,2012Eupatorium odoratum.]]>599106