Research Journal of Phytochemistry1819-34712151-6081Science International10.3923/rjphyto.2009.18.24Pongamia pinnata in Alloxan Induced Diabetic Mice]]>BadoleSachin L. BodhankarSubhash L. 1200931Pongamia pinnata (L.) Pierre (Fabacae) has been used in traditional medicine for treatment of diabetes. The aim of the research was to study the antihyperglycaemic activity of cycloart-23-ene-3β, 25-diol (code name compound B2) isolated by column chromatography method from stem bark of Pongamia pinnata in alloxan induced diabetic mice. The structure of compound B2 was elucidated by spectroscopical data. Diabetes was induced in mice by alloxan (80 mg kg-1, i.v.). Compound B2 was administered orally. Serum glucose level was determined at 0, 2, 4, 6 and 24 h. The onset was at 2nd h; peak effect at 6th h and the antihyperglycaemic effect was sustained until 24th h. Results obtained in the present study indicated antihyperglycaemic activity of cycloart-23-ene-3β,25-diol (B2).]]>Alam, S.,200451447452Badole, S.L. and S.L. Bodhankar,2009Pongamia pinnata on serum glucose level in diabetic mice.]]>2009Carcache-Blanco, E.J., Y.H. Kang, E.J. Park, B.N. Kardono and L.B.S. Su et al.,2003Pongamia pinnata with the potential to induce quinone reductase.]]>6611971202Chatterjee, A. and S.C. Pakrashi,1992Vol. 2,Djerassi, C. and R. McCrindle,1962Epanish moss (Tillandsia usneoides, L.).]]>140344039Krishnamurthi, A.,1998Li, L., X. Li, C. Shi, Z. Deng, H. Fu, P. Proksch and W. Lin,2006Pongamia pinnata.]]>6713471352Madureira, A.M., J.R. Ascenso, L. Valdeira, A. Duarte, J.P. Frade, G. Freitas and M.J.U. Ferreira,2003Euphorbia segetalis.]]>17375380Pathak, V.P., T.R. Saini and R.N. Khanna,1983Pongamia glabra seeds.]]>2213031304Talapatra, S.K., A.K. Mallik and B. Talapatra,1982Pongamia glabra.]]>21761766Tamrakar, A.K., P.P. Yadav, P. Tiwari, R. Maurya and A.K. Srivastava,2008Pongamia pinnata fruits.]]>118435439Teresa, J.P., J.G. Urones, I.S. Marcos, P. Basabe, J.S. Cuadrado and R.F. Moro,1987Euphorbia brotery.]]>2617671776Yin, H., S. Zhang, J. Wu, H. Nan, L. Long, J. Yang and Q. Li,2006Pongamia pinnata with a modified ring A.]]>11786791Yin, H., S. Zhang, J. Wu and H. Nan,2006Pongamia pinnata.]]>1714321435Tanaka, T., M. Iinuma, Y. Fujii, K. Yuki and M. Mizuno,1992Pongamia pinnata.]]>31993998Yin, H., S. Zang and J. Wu,2004Pongamia pinnata.]]>27493495Asolkar, L.V., K.K. Kakkar and O.J. Chakra,1992pp: 265-266pp: 265-266Joy, P.P., J. Thomos, S. Mathew and B.P. Skaria,1998pp: 73-74pp: 73-74Kirtikar, K.R. and B.D. Basu,1987Vol. 1, 2nd Edn.,pp: 830-832pp: 830-832Kokate, C.K., 19913rd Edn.,pp: 107-113pp: 107-113Badole, S.L. and S.L. Bodhankar,2008Pongamia pinnata stem bark in diabetic mice.]]>46900905