Research Journal of Medicinal Plants1819-34552151-7924Science International10.3923/rjmp.2016.228.236In-vitro Antioxidant and Antimicrobial Activity of Bougainvillea glabra Flower]]>IslamMd. Zahidul HossainMd. Tanvir HossenFoysal AkterMir Salma MokammelMohammad Arif 32016103The aim of the present study is to assess the phytochemical nature, antioxidant and antimicrobial activities of methanolic extract of
Bougainvillea glabra flower. Antioxidants play an important role in protecting cellular damage by reactive oxygen species. The fractions
of the flower extract were screened for antioxidant activities using DPPH radical scavenging activity, reducing power assay, total
antioxidant capacity and reduction of ferric ions by o-phenanthroline color method. Antimicrobial activities of different solvent fractions
were tested against gram positive and gram negative bacterial strains by observing the zone of inhibition using disc diffusion method,
where eImipenem (10 μg disc1) was used as the standard. The bacterial strains used in the study were Staphylococcus aureus ,
Bacillus cereus , Escherichia coli and Pseudomonas aeruginosa. The extracts revealed the presence of phytochemicals. Almost all three
fractions exhibited remarkable antioxidant and antimicrobial activity in terms of all the assays tested. Water fraction showed DPPH radical
scavenging activity with IC50 value of 135.73 μg mL1. Not surprisingly, the n-hexane fraction showed excellent antioxidant activity for
reduction of ferric ions by o-phenanthroline color method. All three types of fractions showed inhibitory effect against all tested bacteria
except P. aeruginosa. These findings indicate compounds isolated from carbon tetrachloride and water fractions possess pharmacological
properties and potential to develop natural compounds based pharmaceutical products. All fractions of B. glabra were found to be the
most effective free radical quencher, a potent source of natural antioxidants and antimicrobial agents, thus justifying their traditional use
in green therapeutics.]]>Adebayo, G.I., O.T. Alabi, B.V. Owoyele and A.O. Soladoye,2009Bougainvillea glabra (Glory of the Garden) on alloxan-induced diabetic rats.]]>3187192Adebayo, J.O., A.A. Adesokan, L.A. Olatunji, D.O. Buoro and A.O. Aoladoye,2005Bougainvillea spectabilis leaves on haematological and serum lipid variables in rats.]]>174550Adeyeye, E.I. and O.O. Ayejuyo, 1994Cola acuminata and Garcinia kola seeds grown in Nigeria.]]>45223230Afroze, F. and M.T. Hossain,2015Psidium guajava leaves growing in coastal area of Bangladesh.]]>4140151Balandrin, M.F., J.A. Klocke, E.S. Wurtele and W.H. Bollinger,198522811541160Balch, J.F. and P.A. Balch,2000pp: 267-270pp: 267-270Bhat, M., S.K. Kothiwale, A.R. Tirmale, S.Y. Bhargava and B.N. Joshi,2011Azardiracta indica and Bougainvillea spectabilis: In vivo studies in murine diabetes model.]]>2011Bolognesi, A., L. Polito, F. Olivieri, P. Valbonesi and L. Barbieri et al.,1997Basella rubra L. and Bougainvillea spectabilis Willd.]]>203422429Dev, U.K., M.T. Hossain and M.Z. Islam,2015Mikania micrantha leaves.]]>4121133Duh, P.D.,1998Arctium lappa Linne): Its scavenging effect on free-radical and active oxygen.]]>75455461Edwin, E., E. Sheeja, E. Toppo, V. Tiwari and K.R. Dutt,2007Bougainvillea glabra Choisy.]]>48135144Joshny, J., R.D. Devi and B.N.V. Hari,2012in-vitro anthelmintic activity of hydro alcoholic extract of Bougainvillea glabra.]]>4115117Hassan, H.S., M.I. Sule, M.A. Usman and A. Ibrahim,2009Bauhinia rufescence Lam using some selected pathogens.]]>25355Hossain, M.T.,2015Sarcochlamys pulcherrima leaves.]]>4274283Hossen, F., M.M.O. Rashid, M.M. Alam, M.S. Akter, M.T. Hossain and K.N. Akhter,2015Areca catechu L. fruit extract loaded silver nanoparticles.]]>4258266Ikegami, F., Y. Fujii, K. Ishihara and T. Satoh,2003145235250Izzo, A.A.,2004Hypericum perforatum): A review of the clinical evidence.]]>42139148Jisaka, M., H. Ohigashi, T. Takagaki, H. Nozaki and T. Tada et al.,19921, A2 and A3 and related B1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees.]]>48625632Jones, F.A.,1996812271231Kahkonen, M.P., A.I. Hopia, H.J. Vuorela, J.P. Rauha, K. Pihlaja, T.S. Kujala and M. Heinonen,19994739543962Kumarasamy, Y., M. Byres, P.J. Cox, M. Jaspars, L. Nahar and S.D. Sarker,200721615621Madziga, H.A., S. Sanni and U.K. Sandabe,2010Acalypha wilkesiana leaf.]]>6510514Malomo, S.O., J.O. Adebayo, R.O. Arise, F.J. Olorunniji and E.C. Egwim,2006Bougainvillea spectabilis leaves on some liver and kidney function indices in rats.]]>17261272Mariajancyrani, J., G. Chandramohan, M.F. Beevi and A. Elayaraja,2013Bougainvillea glabra choicy leaves.]]>17275Maurya, R., G. Singh and P.P. Yadav,200835517545Mishra, N., S. Joshi, V.L. Tandon and A. Munjal,2009Bougainvillea spectabilis leaves in Swiss albino mice.]]>11923Oktay, M., I. Gulcin and O.I. Kufrevioglu,2003in vitro antioxidant activity of fennel (Foeniculum vulgare) seed extracts.]]>36263271Oyaizu, M.,198644307316Perales, Y.J. and M. Leysa,2012Bougainvillea glabra plant extract as potential sources of antibacterial and resistance-modifying agents.]]>2012pp: 121125Prieto, P., M. Pineda and M. Aguilar,1999269337341Al-Reza, S.M., V.K. Bajpai and S.C. Kang,2009Zizyphus jujuba.]]>4723742380Saikia, H. and A. Lama,2011Bougainvillea spectabilis leaves on serum lipids in albino rats fed with high fat diet.]]>3141145Satish, S., K.A. Raveesha and G.R. Janardhana,1999Xanthomonas campestris pathovars.]]>28145147Sudha, G., M.S. Priya, R.I. Shree and S. Vadivukkarasi,2011In vitro free radical scavenging activity of raw pepino fruit (Solanum muricatum).]]>3137140Takao, T., F. Kitatani, N. Watanabe, A. Yagi and K. Sakata,19945817801783Tapsell, L.C., I. Hemphill, L. Cobiac, C.S. Patch and D.R. Sullivan et al.,2006185S4S24Wang, M., J. Li, M. Rangarajan, Y. Shao, E.J. LaVoie, T.C. Huang and C.T. Ho,1998Salvia officinalis).]]>4648694873Yen, C.C. and P.D. Duh,199370383386Yosef, S., L.J. Raymond and C.M. Gunter,200165300303