Research Journal of Medicinal Plants1819-34552151-7924Science International10.3923/rjmp.2015.42.47Piper nigrum Linn.) Extract on Sexual Drive in Male Mice]]>Sutyarso KanediM. RosaE. 1201591Black pepper (Piper nigrum L.), known as the king of spices, proven to contain various types of active substances that are allegedly beneficial to the human body functions including sexual function. This study was conducted to determine whether black pepper extract can be used to improve sexual function in male subjects. Thirty six healthy male mice, four months old, weighing between 25-30 g, were used as experimental animals and grouped into four. The first one mice was given pellets that do not contain black pepper extract as a control. The second and third groups, respectively were treated with pellets containing aqueous and ethanol extracts. The last group was given pellets containing aqueous extract and ethanolic extracts with a ratio of 1:1. Pellets were given once every day for 90 days. Mating behavior test was conducted in an open round plastic tray with a diameter of 40 cm and height 25 cm. Throughout the test, videotaping was performed for the following parameters: courtship latency and mounting frequency. The results revealed that compared with control group, male mice fed on aqueous as well as ethanol extract of black pepper significantly showed a shorter courtship latency (p<0.05). On the other hand, there was no difference in the mounting frequency between treated groups. Interestingly, the mounting frequency showed a strong negative correlation with the courtship latency (r = -0.968). In conclusion, the fruit extract of black pepper potentially affect sexual drive in male mice.]]>Acharya, S.G., A.H. Momin and A.V. Gajjar,201223244Ahmad, N., H. Fazal, B.H. Abbasi, S. Farooq, M. Ali and M.A. Khan,2012Piper nigrum L. (Black pepper): A review.]]>2S1945S1953Ali, H., M. Ahmed, M. Baig and M. Ali,200723111114Bassey, E., C. Jackson, A. Aquaisua, E. Bassey and G. Ekpe,2011Piper nigrum on stomach of wistar rat.]]>26873Bouba, A.A., N.Y. Njintang, H.S. Foyet, J. Scher, D. Montet and C.M.F. Mbofung,20123423432Brilla, L.R. and V. Conte,200032636Chanda, D., K. Shanker, A. Pal, S. Luqman, D.U. Bawankule, D. Mani and M.P. Darokar,20093499108Clancy, A.N., A.Coquelin, F. Macrides, R.A. Gorski and E.P. Nobles,1984422222229D'Cruz, S.C. and P.P. Mathur,20057363368Egwurugwu, J.N., C.U. Ifedi, R.C. Uchefuna, E.N. Ezeokafor and E.A. Alagwu,2013281722Gromadzka-Ostrowska, J.,200661320Hamza, S., V. Srinivasan and R. Dinesh,2007Piper nigrum L.) gardens in Kerala and Karnataka.]]>167781Hirata, N., M. Tokunaga, S. Naruto, M. Iinuma and H. Matsuda,2007Piper nigrum leaf.]]>3024022405Ismail, M.M., T.M. Essam, A.F. Mohamed and F.E. Mourad,20123200207Khani, M., R.M. Awang, D. Omar and M. Rahmani,2013Piper nigrum L. and Jatropha curcas L. extracts against rice moth, Corcyra cephalonica (Stainton).]]>712551262Kpomah, E.D., A.A. Uwakwe and B.W. Abbey,2012Zanthoxylum leprieurii Guill. & Perr. and Piper guineense Schumach. & Thonn. on male wistar rats.]]>1381390Kumar, P., B. Yadav and S. Yadav,20134 and T3 level in goat blood serum.]]>41382386Meghwal, M. and T.K. Goswami,20122012Mishra, R.K. and S.K. Singh,2009Piper nigrum L. in mice.]]>47706714Mishra, R.N.,20122197207Naseri, M.K.G. and H. Yahyavi,200763540Nkansah, M.A. and C.O. Amoako,2010Kumasi metropolis of Ghana.]]>1158163Nwaopara, A.O., C.I.P. Anibeze and F.C. Akpuaka,200912125Rahmawati, N. and M.S. Bachri,2012Piper retrofractum L, Centella asiatica and Curcuma domestica infusion.]]>31922Sawidis, T., L. Yurukova and T. Askitis,2010484854Vijayakumar, R.S. and N. Nalini,2006Piper nigrum, modulates hormonal and apolipoprotein profiles in hyperlipidemic rats.]]>177186Wallen, K.,200140339357