Research Journal of Medicinal Plants1819-34552151-7924Science International10.3923/rjmp.2013.82.91 Parkia biglobosa (Jacq) Benth]]>AsekunO.T.OkohS.O.FamiloniO.B.AfolayanA.J.2201372Natural antioxidants have been proven safe and potent for the treatment and
prevention of several human diseases. This study aimed to investigate the chemical
profiles and antioxidant activities of essential oils extracted from the leaf
and stem of Parkial biglobosa (Jacq) Benth. The leaf and stem of the
plant were subjected to hydro-distillation (modified Clevenger apparatus) to
obtain essential oils analyzed by GC/MS method. The antioxidant activities of
the oils were determined by evaluating their scavenging activities against DPPH,
ABTS and nitric oxide using different concentrations (0.5, 0.2, 0.05 and 0.025
mg mL-1). Positive controls were vitamin C and rutin. The essential
oils extracted from the leaf and stem contained 34 and 15 constituents accounting
for 84.9 and 95.9% of the total oil, respectively. Of the 34 eluted, 33 compounds
were identified in the leaf essential oil. The major components were limonene
(16.0%), hexadecanoic acid (12.5%) and farnesene (10.2%). Thirteen compounds
were identified in the stem oil, the major compounds were caryophyllene oxide
(16.6%), β-caryophyllene alcohol (14.9%), terpinene-4-ol (12.1%) and β-caryophyllene
(8.1%). The three antioxidant assays were concentration dependent with varying
antioxidant potentials. The antioxidant activity of the stem and stem oils were
similar to that of the standard drugs used. The present findings suggest that
the essential oils obtained from the leaf and stem of P. biglobosa posses
strong antioxidant potential and can be used to produce natural antioxidants
as well as natural food preservatives.]]>Amer, A. and H. Mehlhorn,2006Parasitol. Res.,99478490Adlard, E.R. and J. Alan,2001Gas Chromatographic Techniques and Applications.pp: 3-7pp: 3-7Agunu, A., S. Yusuf, G.O. Andrew, A.U. Zezi and E.M. Abdurahman,2005J. Ethnopharmacol.,1012730Ahmed, I., M. Zahin, F. Agil, S. Hasan, M.S.A. Khan and M. Owais,2008Punica Granatun, Curuma longa and Zingibere and their therapeutic potentials.]]>Drugs Fut.,33329330Alabi, D.A., O.R. Akinsulire and M.A. Sanyaolu,2005Parkia biglobosa (Jacq) Benth.]]>Afr. J. Biotechnol.,4812815Burits, M. and F. Bucar,2000Nigella sativa essential oil.]]>Phytother. Res.,14323328Dessy, C. and O. Feron,2004Curr. Med. Chem. Anti-Inflammatory Anti-Allergy Agents,3207216Emami, S.A., M. Fakhrjafary, M. Tafaghodi and M. K. Hassanzadeh,2010Cupressus arizonica greene.]]>J. Essent. Oil Res.,22193199Farag, R.S., A.Z.M.A. Badei, F.M. Hewedi and G.S.A. El-Baroty,1989J. Am. Oil Chem. Soc.,66792799Foti, M.C. and K.U. Ingold,2003J. Org. Chem.,6891629175Sacchetti, G., S. Maietti, M. Muzzoli, M. Scaglianti, S. Manfredini, M. Radice and R. Bruni,2005Food Chem.,91621632Grassmann, J., S. Hippeli, R. Spitzenberger and E.F. Elstner,2005Pinus mugo L. in concert with alpha-tocopherol and beta-carotene effectively prevents oxidation of LDL.]]>Phytomedicine,12416423Halliwell, B. and J.M.C. Gutteridge,1989Free Radicals in Biology and Medicine.2nd Edn.,pp: 416-493pp: 416-493Hou, Y.C., A. Janczuk and P.G. Wang,1999Curr. Pharm. Des.,5417441Huang, H.L., C.C. Chen, C.Y. Yeh and R.L. Huang,2005J. Ethnopharmacol.,972129Hyun, E., M. Bolla, M. Steinhoff, J.L. Wallace, P. Del Soldato and N. Vergnolle,2004British J. Pharmacol.,143618625Kaurinovic, B., Vlaisavljevic, S., M. Popovic, D. Vastag and M. Djurendic-Brenesel,2010Marrubium peregrinum L. (Lamiaceae) Essential Oil.]]>Molecules,1559435955Millogo-Kone, H., I.P. Guissou, O. Nacoulm and A.S. Traore,2006Parkia biglobosa (Jacq.) Benth on Staphylococcus aureus.]]>Afr. J.Traditional Complem. Alter. Med.,37478Misharina, T.A. and A.L. Samusenko,2008Applied Biochem. Microbiol.,44438442Murray, A.P., S. Rodriguez, M.A. Frontera, M.A. Tomas and M.C. Mulet,2004Limonium brasiliense (Boiss.) Kuntze.]]>Z. Naturforsch C,59477480Mimica-Dukic, N., D. Bugarin, S. Grbovic, D. Mitic-Culafic and B.Vukovic-Gacic et al.,2010Myrtus communis L. as a potential antioxidant and antimutagenic agents.]]>Molecules,1527592770Nweze, E.I. and J.I. Okafor,2010Scedosporum apiospermum islotates.]]>Am. Eurasian J. Scient. Res.,5161169Odetola, A.A., O. Akinloye, C. Egunjobi, W.A. Adekunle and A.O. Ayoola,2006Parkia biglobosa (JACQ) extract in alloxan-induced diabetic rats.]]>Clin. Exp. Pharmacol. Physiol.,33808812Peana, A.T., S.Marzocco, A. Popolo and A. Pinto,2006in vitro NO formation: Probable involvement in the antinociceptive activity of this monoterpene compound.]]>Life Sci.,78719723Re, R., N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans,1999Free Radical Biol. Med.,2612311237Yang, S.A., S.K. Jeon, E.J. Lee, C.H. Shim and I.S. Lee,2010Nat. Product Res.: Formerly Nat. Product Lett.,24140151Sreejayan and M.N.A. Rao,1997J. Pharm. Pharmacol.,49105107US Pharmacopeia,2007U.S pharmacopeia national formulary.2007Nantitanon, W., S. Chowwanapoonpohn and S. Okonogi,2007Hyptis suaveolens essential oil.]]>Sci. Pharm.,753546Yanishlieva, N.V., E.M. Marinova, H.M. Gordon and V.G. Raneva,1999Food Chem.,645966