Research Journal of Environmental Toxicology1819-3420xxxx-xxxxAcademic Journals Inc.10.3923/rjet.2018.56.62Steven OnwukweOkechukwu Chinonyelum AzubikeNkiruka Kachi UdeaniTheophilus Obianuju OnyemelukweAnulika Florence ChukwuaguChidera Uwadiegwu AchukwuPeter 22018122Background and Objectives: Welders are often occupationally exposed to potentially harmful substances. This study assessed the haematological profile and the frequency buccal cell nuclear abnormalities of automobile welders who use calcium carbide as a source of fuel in Enugu, Nigeria. Materials and Methods: A total of 50 participants (30 automobile welders and 20 controls) were recruited for the study. Questionnaires were used to obtain participant’s bio data and exposure characteristics. Haematological parameters were measured and assessment of buccal cell nuclear abnormalities was done by cytological evaluation of participants’ the buccal cells. Results: The welders were observed to had significantly lower total red blood cells and haemoglobin concentration. They also had significantly higher micronuclei frequency compared to the control group. Further analysis showed that number of years spent in the occupation, alcohol consumption and ongoing medications significantly affected the frequency of micronuclei among the welders. Conclusion: Automobile welders may be exposed to toxic substances which may cause increased frequency of micronuclei and reduced red cell count and haemoglobin concentration.]]>Isah, E.C. and O.H. Okojie,200656469ILO.,1968Golbabaei, F. and M. Khadem,20152015Bhumika, T.V., M. Thakur, R. Jaswaf, P. Pundir and E. Rajwar,20152015Antonini, J.M.,20083361103Chadha, P. and Z. Singh,20132013IARC.,19901990Umoren, Q.M., U.S. Ekanem, O.E. Johnson and M.O. Olugbemi,2016332203228Sabitu, K., Z. Iliyasu and M.M. Dauda,200984651Adewoye, K.R., A.O. Awoyemi, D.O. Ibirongbe, O.A. Babatunde and T. Ibrahim,20133924932Eze, B.I., O. Okoye and E.N. Aguwa,201563170178Ashraf Ur-Rahman, F.R. Chowdhury and M.B. Alam,200894244Ogbuagu, D.H., C.O. Ujowundu and C.L. Izunobi,2016Mus musculus.]]>10100104Okolie, N.P., R.I. Ozolua and D.E. Osagie,200552125Haturusihghe, L.S., D.S.M. De Silva and S. Wimlasena,20042004Sage, A.P., B.C. Minatel, K.W. Ng, G.L. Stewart, T.J. Dummer, W.L. Lam and V.D. Martinez,201782573625755Gradecka, D.O.B., J.A.D. Palus and W. Wasowicz,200114317328Shakoor, M.B., R. Nawaz, F. Hussain, M. Raza and S. Ali et al.,2017601756769Andrew, G.S., U.T. Simon, A.U. John, O.O. Godwin, N.I. Alexander and Y.M. Ikagu,201882736Bayer, F.J. and R.E. Silerton,1966Tolbert, P.E., C.M. Shy and J.W. Allen,1991134840850Saha, J.C., A.K. Dikshit, M. Bandyopadhyay and K.C. Saha,199929281313Ibeh, N., J. Aneke, C. Okocha and E. Obeagu,201656670Kuo, C.H., K.C. Wang, T.F. Tian, M.H. Tsai and Y.M. Chiung et al.,201225676686Croft, D.P., S.J. Cameron, C.N. Morrell, C.J. Lowenstein and F. Ling et al.,2017154352361Wultsch, G., A. Nersesyan, M. Kundi, K.H. Wagner, F. Ferk, R. Jakse and S. Knasmueller,201530701709Bolognesi, C., S. Bonassi, S. Knasmueller, M. Fenech, M. Bruzzone, C. Lando and M. Ceppi,20157662031Sudha, S., S.K. Kripa, P. Shibily, S. Joseph and V. Balachandar,20111210411044Jara-Ettinger, A.C., J.C. Lopez-Tavera, M.G. Zavala-Cerna and O. Torres-Bugarin,20152015Shaikh, A., D. Barot and D. Chandel,2018911591179Benedetti, D., E. Nunes, M. Sarmento, C. Porto, C.E.I. dos Santos, J.F. Dias and J. da Silva,20137522833Holland, N., C. Bolognesi, M. Kirsch-Volders, S. Bonassi, E. Zeiger, S. Knasmueller and M. Fenech,200865993108Machado-Santelli, G.M., E.M. Cerqueira, C.T. Oliveira and C.A.A. de Braganca Pereira,1994322203208