Plant Pathology Journal1812-53871812-5425Asian Network for Scientific Information10.3923/ppj.2007.72.76Sechium edule) Extract on the Plasmid Puc. 9.1 DNA]]>DireG.F. CouraM.F.M.C. AlmeidaM.C.L. VasconcelosS.D.D. SiqueiraP.R.A. DuarteR.M. RodriguesJ.S. OliveiraJ.C.S. FernandesM.L. Bernardo-FilhoM. 1200761Stannous chloride (SnCl2) is employed as a reducing agent to obtain Technetium-99m-labelled radiopharmaceuticals in nuclear medicine kits, being inject endogenously in humans. Toxic effects of. these kits were not studied, thus making it important to evaluate their impact in humans. The use of natural extracts as medicines is growing around the world. The chayotte (Sechium edule) is a subtropical vegetable with potent diuretic action. It is used in folk medicine due its hypotensor effect. In this study, plasmid deoxyribonucleic acid (DNA) was exposed to chayotte extracts (macerated) (0.1g mL-1) in presence of stannous chloride (SnCl2). Samples of the plasmid DNA were analyzed through agarose gel electrophoresis. The results show that the chayotte extract was capable of damaging the DNA in the presence and in the absent of SnCl2.]]>Aherne, S.A. and M.N.O. Brien,199934160166Ashby, J. and R.W. Tennant,1991257229306Bernardo-Filho, M., M.C. Cunha, J.O. Valsa, A.C. Araujo, F.C.P. Silva and A.S. Fonseca,1994Escherichia coli.]]>32477479Bernardo, L.C., M.B.N. Oliveira, C.R. Silva, F.J.S. Dantas and J.C.P. Mattos et al.,2002Escherichia coli AB 1157 and on the electrophoretic mobility of plasmid PUC 9.1 DNA.]]>48517520Bettger, W.J. and B.L.A.O. Dell,19812814251438Budavery, S.,1996pp: 1500-1501pp: 1500-1501Cabral, R.E., A.C. Leitao, C. Lage, A. Caldeira-de-Araujo, M. Bernardo-Filho, F.J. Dantas and J.B. Cabral-Neto,1998408129135Caldeira de Araujo, A., F.J.S. Dantas, M.O. Moraes, I. Felzenszwalb and M.B. Filho,199648109113Capasso, R., A.A. Izzo, L. Pinto, T. Bifulco, C. Vitobello and M. Mascolo,200071S58S65Cunha Bastos, V.L.F., J.F. Cunha Bastos and J.S. Lima,1991in vitro detector of organophosphorus and carbamate insectides in the water.]]>7835840Dantas, F.J.S., M.O. Moraes, J.C.P. De Mattos, R.J.A.C. Bezerra, E.F. Carvalho, M.B.D. Filho and A.C. Araujo,1999110129136Dire, G., E. Lima, D. Mattos, M.B. Oliveira and M.J. Pereira et al.,2001Sechium edule) extract on the biodistribution of technetium 99m and on the morphometry of red blood cells.]]>44648650Dantas, F.J.S., M.O. Moraes, E.F. Carvalho, J.O. Valsa, M.B. Filho and A.C.D. Araujo,1996Escherichia coli AB1157 participation of reactive oxygen species.]]>34959962Dire, G.D., E.A.C. Lima, M.J.S. Pereira, M.B.N. Oliveira and S.R.F. Moreno et al.,2002Sechium edule) extract on the labeling of red blood cells and plasma proteins with technetium-99m: In vitro and in vivo studies.]]>48751755Felzenszwalb, I., J.C.P.D. Mattos, M.B. Filho and A.C.D. Araujo,19983610791084Gleason, M.N., R.E. Gosselin, C.H. Hodge and R.P. Smith,1969Gordon, E.A.,200012731Gutteridge, J.M.C., G.J. Quilan, I. Clarke and B. Hallinwell,1985835441447Hallas, L.E. and J.J. Cooney,198141466471Halliwell, B.,199452253265Hladik III, W.B., G.B. Saha and K.T. Study,1987Jensen, L.P. and A.R. Lai,1986Sechium edule) causing hypokalemia in pregnancy.]]>15510481049Lima, E.A.C., G. Dire, D.M.M. Mattos, M.N. de Oliveira and J.C.P. Mattos et al.,2001Brassica oleracea L. Var. Botrytis) on the biodistribution of the radiopharmaceutical sodium pertechnetate in mice and on the electrophoretic mobility of plasmid pUC 9.1 DNA.]]>44S642S644Leite, J.R., L. Seabra Mde, E. Maluf, K. Assolant and D. Suchecki et al.,1986Cymbopogon citratus Stapf). III. Assessment of eventual toxic hypnotic and anxiolytic effects on humans.]]>177583Lima, E.A.C., G. Dire, D.M.M. Mattos, R.S. Freitas and M.L. Gomes et al.,2002Escherichia coli AB1157 submitted to the treatment with stannous chloride.]]>40919923McLean, J.R.N., D.H. Blakey, G.R. Douglas and J.R. Kaplan,1983119195201Melo, S.F., S.F. Soares, R.F. Costa, C.R. Silva and M.B.N. Oliveira et al.,2001Escherichia coli.]]>4963338Moro, C.O. and G. Basile,200071S73S82Oliver, P. and D. Marzin,1987189263269Orsolic, N., S. Terzic, Z. Mihaljevic, L. Sver and I. Basic,20052819281933Rader, J.I.,1991289509524Reiniger, I.W., C.R. Silva, I. Felzenszwalb, J.C.P. Mattos and J.F. Oliveira et al.,199968345348Salle, J.L.O.,19961996Silva, C.R., M.B.N. Oliveira, S.F. Melo, F.J.S. Dantas and J.C.P. Mattos et al.,200259213216Singh, I.,1983Saccharomyces cerevisae.]]>117149152Stohs, S.J. and D. Bagchi,199518321336Triphaty, N.K., F.E. Wurgler and H. Frei,1990Drosophila wing spot test.]]>242169180Wood, J.M.,197418310491052