Pakistan Journal of Nutrition1680-51941994-7984Asian Network for Scientific Information10.3923/pjn.2016.397.405Moringa oleifera Lam and its Potential Use as Nutraceutical Plant: A Review]]>Godinez-OviedoA. Guemes-VeraN. Acevedo-SandovalO.A. 42016154Moringa oleifera Lam. is a plant that is known for its nutritional value and particularly for its protein quantity and quality. Due to its nutrient constitution, M. oleifera is used in several regions to treat malnutrition, especially in children. Moreover, M. oleifera contains phytochemical compounds that have important biological activities. Several previous studies confirmed that extracts or compounds isolated from M. oleifera have antioxidant, anti-carcinogenic, anti-diabetic, anti-inflammatory and anti-hypertensive properties, as well as the ability to protect against hepatic damage. This review discusses the characteristics and potential benefits of M. oleifera nutrients and phytochemicals.]]>Abdulkarim, S.M., K. Long, O.M. Lai, S.K.S. Muhammad and H.M. Ghazali,200593253263Abdulkarim, S.M., K. Long, O.M. Lai, S.K.S. Muhammad and H.M. Ghazali,200710513821389Adedapo, A.A., O.M. Mogbojuri and B.O. Emikpe,2009Moringa oleifera in rats.]]>3586591Akinlolu, A.A., O.K. Ghazali, O.M. Ameen, S.C. Oyebanji, G.O. Omotoso and B.U. Enaibe,2014Moringa oleifera impairs the morphology and functions of the kidney in adult wistar rats.]]>32469474Alhakmani, F., S. Kumar and S.A. Khan,2013in-vitro antioxidant and anti-inflammatory activity of flowers of Moringa oleifera.]]>3623627Al‐Said, M.S., R.A. Mothana, M.A. Al‐Yahya, A.S. Al‐Blowi, M. Al‐Sohaibani, A.F. Ahmed and S. Rafatullah,2012Moringa oleifera seed oil against chemical‐induced hepatitis in rats.]]>77T124T130Anjorin, T.S., P. Ikokoh and S. Okolo,2010Moringa oleifera leaves, pods and seeds from two regions in Abuja, Nigeria.]]>12431434Anwar, F. and M.I. Bhanger,2003Moringa oleifera seed oil grown in temperate regions of Pakistan.]]>5165586563Anwar, F., M. Ashraf and M.I. Bhanger,2005Moringa oleifera oilseeds from Pakistan.]]>824551Anwar, F., S. Latif, M. Ashraf and A.H. Gilani,2007Moringa oleifera: A food plant with multiple medicinal uses.]]>211725Ashfaq, M., S.M.A. Basra and U. Ashfaq,20128115122Aslam, M., F. Anwar, R. Nadeem, U. Rashid, T.G. Kazi and M. Nadeem,2005Moringa oleifera leaves and pods from different regions of Punjab, Pakistan.]]>4417421Atawodi, S.E., J.C. Atawodi, G.A. Idakwo, B. Pfundstein and R. Haubner et al.,2010Moringa oleifera Lam.]]>13710716Banerji, R., S.C. Verma and P. Pushpendra,2003Moringa.]]>26869Bennett, R.N., F.A. Mellon, N. Foidl, J.H. Pratt, M.S. Dupont, L. Perkibns and P.A. Kroon,2003Moringa oleifera L. (Horseradish Tree) and Moringa stenopetala L.]]>5135463553Berkovich, L., G. Earon, I. Ron, A. Rimmon, A. Vexler and S. Lev-Ari,2013Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells.]]>2013Bharali, R., J. Tabassum and M.R. Azad,2003Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice.]]>4131139Teixeira, E.M.B., M.R.B. Carvalho, V.A. Neves, M.A. Silva and L. Arantes-Pereira,2014Moringa oleifera Lam. leaves.]]>1475154Cheenpracha, S., E.J. Park, W.Y. Yoshida, C. Barit, M. Wall, J.M. Pezzuto and L.C. Chang,20101865986602Chumark, P., P. Khunawat, Y. Sanvarinda, S. Phornchirasilp and N.P. Morales et al.,2008in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves.]]>116439446Costa-Lotufo, L.V., M.T.H. Khan, A. Ather, D.V. Wilke and P.C. Jimenez et al.,2005992130Das, N., K. Sikder, S. Ghosh, B. Fromenty and S. Dey,2012Moringa oleifera Lam. leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet.]]>50404412Dhakar, R.C., S.D. Maurya, B.K. Pooniya, N. Bairwa and M. Gupta,2011Moringa: The herbal gold to combat malnutrition.]]>2119125Fahey, J.W.,2005Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part 1.]]>2005Faizi, S., B.S. Siddiqui, R. Saleem, K. Aftab, F. Shaheen and A.H. Gilani,1998Moringa oleifera.]]>64225228Faizi, S., B.S. Siddiqui, R. Saleem, S. Siddiqui and K. Aftab et al.,19945712561261Faizi, S., B.S. Siddiqui, R. Saleem, S. Siddiqui, K. Aftab and A.H. Gilani,1995Moringa oleifera.]]>38957963Fakurazi, S., I. Hairuszah and U. Nanthini,2008Moringa oleifera lam prevents acetaminophen induced liver injury through restoration of glutathione level.]]>4626112615Fakurazi, S., U. Nanthini and H. Ithnin,2008Moringa oleifera Lam. againsts acetaminophen induced hepatoxicity in rats.]]>4270275Ferreira, P.M.P., D.F. Farias, J.T.D.A. Oliveira and A.D.F.U. Carvalho,2008Moringa oleifera: Bioactive compounds and nutritional potential.]]>21431437Ghasi, S., E. Nwobodo and J.O. Ofili,2000Moringa oleifera Lam in high-fat diet fed wistar rats.]]>692125Guevara, A.P., C. Vargas, H. Sakurai, Y. Fujiwara and K. Hashimoto et al.,1999Moringa oleifera Lam.]]>440181188Gupta, R., M. Mathur, V.K. Bajaj, P. Katariya, S. Yadav, R. Kamal and R.S. Gupta,2012Moringa oleifera in experimental diabetes.]]>4164171Hamza, A.A.,2010Moringa oleifera Lam seed extract on liver fibrosis in rats.]]>48345355Hukkeri, V.I., C.V. Nagathan, R.V. Karadi and B.S. Patil,2006Moringa oleifera Lam. in rats.]]>68124126Iqbal, S. and M.I. Bhanger,2006Moringa oleifera leaves grown in Pakistan.]]>19544551Jain, P.G., S.D. Patil, N.G. Haswani, M.V. Girase and S.J. Surana,2010Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats.]]>20969973Jaiswal, D., P.K. Rai, A. Kumar, S. Mehta and G. Watal,2009Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats.]]>123392396Jaiswal, D., P.K. Rai, S. Mehta, S. Chatterji and S. Shukla et al.,2013Moringa oleifera in regulation of diabetes-induced oxidative stress.]]>6426432Jung, I.L.,2014Moringa oleifera leaves with a new anticancer activity.]]>2014Karadi, R.V., N.B. Gadge, K.R. Alagawadi and R.V. Savadi,2006Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats.]]>105306311Kashiwada, Y., F.A. Ahmed, S.I. Kurimoto, S.Y. Kim, H. Shibata, T. Fujioka and Y. Takaishi,2012Moringa oleifera Lam.]]>66217221Kasolo, J.N., G.S. Bimenya, L. Ojok, J. Ochieng and J.W. Ogwal-Okeng,2010Moringa oleifera leaves in Ugandan rural communities.]]>4753757Kumar, N.A. and L. Pari, 2003Moringa oleifera Lam. (Drumstick) against antitubercular drugs induced lipid peroxidation in rats.]]>6255259Kumari, D.J.,2010Moringa oleifera and Azadirachta indica in type 2 diabetes mellitus.]]>5211214Kumbhare, M.R., V. Guleha and T. Sivakumar,2012in-vitro antioxidant activity of stem bark of Moringa oleifera.]]>2144150Lalas, S. and J. Tsaknis,2002Moringa oleifera seed oil variety Periyakulam 1.]]>156577Lalas, S. and J. Tsaknis,2002Moringa oleifera tree variety of Malawi.]]>79677683Mahajan, S.G., R.G. Mali and A.A. Mehta,2007Moringa oleifera Lam. against inflammation associated with development of arthritis in rats.]]>43947Makkar, H.P.S. and K. Becker,1996Moringa oleifera leaves.]]>63211228Mehta, A. and B. Agrawal,2008Moringa oleifera for its anti-asthmatic activity.]]>82431Mehta, L.K., R. Balaraman, A.H. Amin, P.A. Bafna and O.D. Gulati,2003Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits.]]>86191195Mensah, J.K., B. Ikhajiagbe, N.E. Edema and J. Emokhor,2012Moringa oleifera (Lam) from Edo Central province, Nigeria.]]>2107112Morton, J.F.,1991Moringa pterygosperma (Moringaceae): A boon to arid lands?]]>45318333Moyo, B., P.J. Masika, A. Hugo and V. Muchenje,2011Moringa oleifera Lam.) leaves.]]>101292512933Muangnoi, C., P. Chingsuwanrote, P. Praengamthanachoti, S. Svasti and S. Tuntipopipat,2012Moringa oleifera pod inhibits inflammatory mediator production by lipopolysaccharide-stimulated RAW 264.7 murine macrophage cell lines.]]>35445455Ndong, M., M. Uehara, S.I. Katsumata and K. Suzuki,2007Moringa oleifera Lam on glucose tolerance in Goto-Kakizaki and Wistar rats.]]>40229233Nikkon, F., Z.A. Saud, M.H. Rahman and M.E. Haque,2003In vitro antimicrobial activity of the compound isolated from chloroform extract of Moringa oleifera Lam.]]>618881890Oduro, I., W.O. Ellis and D. Owusu,2008Moringa oleifera and Ipomoea batatas leaves.]]>35760Ogbunugafor, H.A., F.U. Eneh, A.N. Ozumba, M.N. Igwo-Ezikpe and J. Okpuzor et al.,2011Moringa oleifera seed oil.]]>10409414Oliveira, J.T.A., S.B. Silveira, I.M. Vasconcelos, B.S. Cavada and R.A. Moreira,1999Moringa oleifera Lamarck.]]>79815820Manguro, L.O.A. and P. Lemmen,2007Moringa oleifera leaves.]]>215668Pari, L. and N.A. Kumar,2002Moringa oleifera on antitubercular drug-induced liver damage in rats.]]>5171177Pari, L. and N.A. Kumar,2002Moringa oleifera on antitubercular drug-induced liver damage in rats.]]>5171177Ramachandran, C., K.V. Peter and P.K. Gopalakrishnan,1980Moringa oleifera): A multipurpose Indian vegetable.]]>34276283Rashid, U., F. Anwar, B.R. Moser and G. Knothe,2008Moringa oleifera oil: A possible source of biodiesel.]]>9981758179Richter, N., P. Siddhuraju and K. Becker,2003Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.).]]>217599611Sashidhara, K.V., J.N. Rosaiah, E. Tyagi, R. Shukla, R. Raghubir and S.M. Rajendran,2009Moringa oleifera as potential anti-inflammatory and antinociceptive agents.]]>44432436Siddhuraju, P. and K. Becker,2003Moringa oleifera Lam.) leaves.]]>5121442155Singh, B.N., B.R. Singh, R.L. Singh, D. Prakash, R. Dhakarey, G. Upadhyay and H.B. Singh,2009Moringa oleifera.]]>4711091116Singh, R.S.G., P.S. Negi and C. Radha,2013Moringa oleifera seed flour.]]>518831891Sreelatha, S. and P.R. Padma,2009Moringa oleifera leaves in two stages of maturity.]]>64303311Sreelatha, S. and P.R. Padma,2010Moringa oleifera against CCl4-induced oxidative stress in precision-cut liver slices.]]>17189194Sreelatha, S., A. Jeyachitra and P.R. Padma,2011Moringa oleifera leaf extract on human cancer cells.]]>4912701275Tree for Life,20052005Verma, A.R., M. Vijayakumar, C.S. Mathela and C.V. Rao,2009In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves.]]>4721962201Vongsak, B., P. Sithisarn, S. Mangmool, S. Thongpraditchote, Y. Wongkrajang and W. Gritsanapan,2013Moringa oleifera leaf extract by the appropriate extraction method.]]>44566571Zvinorova, P.I., L. Lekhanya, K. Erlwanger and E. Chivandi,2015Moringa oleifera leaf powder on growth, gastrointestinal morphometry and blood and liver metabolites in Sprague Dawley rats.]]>992128