Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2020.977.988JamalAdil ShahidImran Naveed ShahidMuhammad Saleh AlshmemriMohammed Saeed BahwerthFayez 82020238Human Papillomavirus (HPV) is sexually transmitted and linked with vaginal, vulvar and cervix cancers in females, penile cancer in male, while anal and oropharyngeal cancer in both genders. Cervical cancer is ranked as third most identified cancer among females globally and is the fourth leading reason of cancer related mortality. The main aim of current study is to highlight the key role of miRNA in cervical cancer development, progression and their therapeutic responses. Current study entailed more than 50 PubMed cited articles related to miRNA role in cervical cancer. Studies have elucidated the role of miRNAs regulation in gene expression at post-transcriptional and translational level by targeting significant genes and therefore involved in cervical cancer. miRNAs control several cellular pathways involved in development of pre-malignant to metastatic stage and proliferation to malignancy. Current review elucidated and elaborated the key role of miRNA their application, treatment and therapeutic responses in cervical cancer.]]>Walboomers, J.M.M., M.V. Jacobs, M.M. Manos, F.X. Bosch and J.A. Kummer et al.,19991891219Forman, D., C. de Martel, C.J. Lacey, I. Soerjomataram and J. Lortet-Tieulent et al.,201230F12F23Munoz, N., F.X. Bosch, S. de Sanjose, R. Herrero and X. Castellsague et al.,2003348518527Zur Hausen, H.,1991184913Devaraj, K., M.L. Gillison and T.C. Wu,200314345362Middleton, K., W. Peh, S. Southern, H. Griffin and K. Sotlar et al.,2003771018610201Schiffman, M., G. Clifford and F.M. Buonaguro,20092009Cogliano, V., R. Baan, K. Straif, Y. 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