Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2017.403.409Achillea biebersteinii Pretreatment on Dimethoate Induced Oxidative Stress in Guinea Pigs Liver]]>Saleh Al-AwthanYahya Ali Al-DuaisMohamed Abdulfatah HazebAmany Ahmed AlrilWaleed 82017208Objective: The present study investigated the influence of Achillea biebersteinii (Ab), a medicinal herb used widely in Yemenis folk medicine as analgesic, antipyretic, against diarrhea and flatulence and for liver diseases, on the liver antioxidant potential of guinea pigs acutely intoxicated with dimethoate pesticide (DM). Materials and Methods: Animals were administered with Ab aqueous extract (50 and 100 mg kg1 b.wt., orally) or silymarin (100 mg kg1 b.wt., orally) for 2 weeks followed by single acute DM administration (80 mg kg1 b.wt., 1/4 of the LD50 orally). Data were analyzed by one-way ANOVA using SPSS. 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