Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2014.1219.1224SanouM. SoubeigaS. T.BationoF. CompaoreT. R.ZohonconT. M.DiattoG. N.OuedraogoP. PietraV. NagaloB. M.BisseyeC. TraoreR. OuedraogoSimporeJ. 1220141712Although, HIV-2 is generally less pathogenic than HIV-1 and
its progression towards AIDS occurs less frequently. HIV-2 remains an important
cause of disease in West Africa. This study aimed to evaluate HIV-1 and HIV-2
prevalence among pregnant women and to describe the demographic and clinical
profile of patients with HIV-2 infection from 2003-2013 at St Camille and General
Lamizana Military Medical Centers. A retrospective investigation was conducted
using 12,287 medical records from patients screened for HIV. To respond to the
lack of data available regarding HIV-2 treatment and also to address the approach
to clinical, biological as well as therapeutic monitoring, 62 HIV-2 infected
patients medical records were
studied. Seroprevalence of 10.6 and 0.14% were obtained, respectively for HIV-1
and HIV-2 among 12,287 women screened during the study period. From the sixty
two (62) HIV-2 patients, the average age was 49.2 years (sex ratio was 0.65).
The weight loss and diarrhea were the major clinical manifestations observed,
respectively 54.8 and 25.8%. Fungi and herpes zoster (shingles) infections were
reported as major opportunistic infections. Also, nearly half of the patients
had more than 60 kg, less than 2% were in WHO stage IV and about 2/3 had a CD4
count bellow 250 cells mm-3. AZT-3TC-IDV/LPV/R was the most prescribed
combination. The gain in weight gain the Body Mass Index (BMI) improvement and
the non-significant increase of the rate of CD4 between 1st (M1) and 24th month
(M24) were observed after treatment with antiviral.]]>De Mendoza, C., E. Caballero, A. Aguilera, M. Piron and R.O. de Lejarazu et al.,201416152159Delarue, S., E. Didier, F. Damond, D. Ponscarme and K. Brengle-Pesce et al.,201358461467HDS-IV.,20102010Eholie, S.P., E. Ehui, E. Aoussi, A. Kakou, P.A. Assemien, E. Bissagnene and A. Kadio,199858204205, (In French)Foca, E., S. Odolini, G. Sulis, S. Calza and V. Pietra et al.,20142014Kagone, T.S., H. Hien, N. Meda, P.S. Diagbouga and A. Sawadogo et al.,201114392398Linguissi, L.S.G., C. Bisseye, T. Sagna, B.M. Nagalo and D. Ouermi et al.,20125991994Matheron, S., F. Damond, A. Benard, A. Taieb and P. Campa et al.,200620459462Ndour, C.T., G. Batista, N.M. Manga, N.F.N. Gueye, N.M.D. Badiane, M. Fortez and P.S. Sow,200636111114, (In French)Palermo, B., R.J. Bosch, K. Bennett and J.M. Jacobson,2011+ T-lymphocyte recovery in HIV-infected men with viral suppression on antiretroviral therapy.]]>12222227Pignatelli, S., J. Simpore, V. Pietra, L. Ouedraogo and G. Conombo et al.,200611350357Simpore, J., V. Pietra, S. Pignatelli, D. Karou and W.M.C. Nadembega et al.,200779873879Simpore, J., V. Pietra, A. Savadogo, S. Pignatelli and J.B. Nikiema et al.,200678148152UNAIDS.,20132013