Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2013.1796.1800Lawsonia inermis]]>ImamHasan MahbubNasir UddinKhanMd. ForhadHanaHumayera KabirSarkerMd. Moklesur Rahman1220131623Previously it was reported elsewhere that Lawsonia inermis have anti-inflammatory and analgesic effect in experimental animals. The in vitro porcine alpha amylase inhibitory effect was investigated of this plant methanolic extracts and consequently hypoglycemic effect by quantitatively determining the maltose from the maltose standard curve while the anti-inflammatory effect by acetic acid induced writhing test in mice. Acarbose (10 μg mL-1) and Diclofenac sodium (20 mg kg-1) were used as reference hypoglycemic and anti-inflammatory drugs, respectively, for this study. The methanolic leaves extract of the plant significantly inhibited (60.97% compared to untreated) enzymatic activity of the amylase at 10 μg mL-1 dose (p<0.05) also reduced the chemically induced nociceptive pain stimuli significantly at all doses (p<0.01). Carbohydrates, glycosides, flavonoids, saponins and tannins were found to have in phytochemical screening of the extract which are thought to bring these effects. For the conclusive purpose, it is suggesting from the result that the pharmacological properties of this Lawsonia inermis can elicit hypoglycemic effect by inhibiting α-amylase enzyme and can reduce neurogenic pain stimulus. It gives the notion that how this group of patient would be therapeutically benefitted by decreasing both these effects by the same agent which is easy available.]]>Alia, B.H., A.K. Bashir and M.O.M. Tanira,1995Lawsonia inermis L. (henna) in rats.]]>51356363Awadh Ali, N.A., W.D. Julich, C. Kusnick and U. Lindequist,200174173179Bello, S.O., I. Bashar, B.Y. Muhammad and P. Onyeyili,2010Lawsonia inermis (Lythraceae).]]>1497502Ceriello, A.,20055417Collier, H.O.J., L.C. Dinneen, C.A. Johnson and C. Schneider,196832295310Gupta, A., A.Q. Saifi, N.T. Modi and N. Mishra,1986Lawsonia inermis leaves.]]>18113114Wellen, K.E. and G.S. Hotamisligil,200511511111119Lavhale, M.S. and S.H. Mishra,2007Ailanthus excelsa: A review.]]>1105113Lin, Y., A.H. Berg, P. Iyengar, T.K. Lam and A. Giacca et al.,200528046174626Mikhaeil, B.R., F.A. Badria, G.T. Maatooq and M.M. Amer,200459468476Miller, G.L.,195931426428Singh, V.K. and U.K. Pandley, 1989Lawsonia inermis against ringworm fungi. ]]>313235