Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2013.1557.1562In Vitro Effect of Nigella sativa Oil on Adult Toxocara vitulorum]]>ShalabyH.A. El-MoghazyF.M. 1220131622Since the integrity of Toxocara vitulorum cuticle is
essential for the nutritive and protective functions, light and scanning electron
microscopic studies were undertaken to assess, for the first time, whether the
Nigella sativa oil (NSO) had any effect on the cuticle of adult T.
vitulorum following incubation in vitro. Differences in response
to NSO action were observed, depending on the used concentration. After 24 h
incubation with 0.5 mg mL-1 NSO, the cuticle of the anterior end
of worms appeared to be slightly more swollen than normal. This swelling became
pronounced and so severe, with lips showed wrinkled cuticular surface and deformed
sensory papillae on increasing the concentration to 1.0 mg mL-1.
With the higher concentration of 1.5 mg mL-1, extensive and severe
disorganization of the cuticle and body musculature was observed. Structural
alterations in the cuticle as observed in the present investigation were thus,
clear indication of nematocidal activity of NSO that could offer a suitable
and cheaper alternative for the more expensive anthelmintics.]]>Abu El-Ezz, N.M.,2005Nigella sativa seeds and diclazuril on coccidiosis in chickens.]]>65137147Abu El Ezz, N.M.,2005Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats.]]>35511523Agarwal, R., M.D. Kharya and R. Shrivastava,1979Nigella sativa Linn.]]>1712641265Akhtar, M.S. and S. Riffat,1991Nigella sativa seeds against cestodes in children.]]>41185187Alvarez, L.I., M.L. Mottier and C.E. Lanusse,20072397104Majdalawieh, A.F., R. Hmaidan and R.I. Carr,2010Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK anti-tumor activity.]]>131268275Bancroft, J., A. Stevens and D. Turner,19964th Edn.,Pages: 740Pages: 740 Challam, M., B. Roy and V. Tandon,2010Lysimachia ramosa (Primulaceae) on helminth parasites: Motility, mortality and scanning electron microscopic observations on surface topography.]]>169214218El Shenawy, N.S., M.F.M. Soliman and S.I. Reyad,2008Nigella sativa as anti-schistosomiasis agents in mice.]]>502936Hanser, E., H. Mehlhorn, D. Hoeben and K. Vlaminck,2002In vitro studies on the effects of flubendazole against Toxocara canis and Ascaris suum.]]>896374Issa, R.M.,2003Nigella sativa (Habbet El baraka) in treatment of some parasitic diseases.]]>24435446Mahmoud, M.R., H.S. El-Abhar and S. Saleh,2002Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice.]]>79111Martin, R.J., A.P. Robertson and H. Bjorn,1997114111124Mashhadian, N.V. and H. Rakhshandeh,2005Nigella sativa extracts against S. aureus, P. aeruginosa and C. albicans.]]>214752Mohamadin, A.M., S. Bassem, A.A. Abdel EI-Aal, A.E. Ahmed and F.A. Al-Abbasi,201098128134Rast, L., S. Lee, S. Nampanya, J.A.L.M.L. Toribio, S. Khounsy and P.A. Windsor,2013Toxocara vitulorum in cattle and buffalo calves in Northern Lao PDR.]]>45539546Schmahl, G., H. Mehlhorn, A. Harder, S. Klimpel and K.J. Krieger,2007Trichuris muris, Angiostrongylus cantonensis) in rodents.]]>1018592Shalaby, H.A., A.H. El Namaky, F.A. Khalil and O.M. Kandil,2012Balanites aegyptiaca fruit on Toxocara vitulorum.]]>183386392Shalaby, H.A., N.M.T. Abu El Ezz, T.K. Farag and H.A.A. Abou-Zeina,2012In vitro efficacy of a combination of ivermectin and Nigella sativa oil against helminth parasites.]]>9465473Shalaby, H.A., S. Abdel-Shafy, K.A. Abdel-Rahman and A.A. Derbala,2009in vitro effect of artemether and albendazole on adult Toxocara canis.]]>105967976Singh, K., S.K. Mishra and A.K. Pruthi,2008222329Tippawangkosol, P., W. Choochote, K. Na-Bangchang, A. Jitpakdi, B. Pitasawat and D. Riyong,2004in vitro effect of albendazole, ivermectin, diethylcarbamazine and their combinations against infective third-stage larvae of nocturnally subperiodic Brugia malayi (Narathiwat strain): scanning electron microscopy.]]>29101108