Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2009.738.741Acinetobacter baumannii]]>JazaniN.H. ZartoshtiM. BabazadehH. Ali-daieeN. ZarrinS. HosseiniS. 92009129The aim of the present study was the evaluation of the antibacterial activity of Fennel essential oil on isolates of Acinetobacter baumannii. Forty eight isolates were collected from clinical specimens from burn wards of hospitals in Tehran, Iran between April and September, 2006. The susceptibility of isolates was determined using a broth microdilution method. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of isolates to Fennel essential oil were determined. The susceptibilities of isolates to different antibiotics were tested using agar disk diffusion method. The rates of resistance were determined to antibiotics as follows: cefazolin 100%, ciprofloxacin 100%, ofloxacin 95.8%, kanamycin 95.8%, carbenicillin 93.7%, ticarcillin 93.7%, piperacillin 88.9%, co-trimoxazole 79.1%, ceftizoxime 75%, gentamicin 70.8%, cefalotin 60.4%, amikacin 52% and imipenem 14.6%. Fennel essential oil possessed antibacterial effect against all isolates of A. baumannii. These results suggest the potential use of the Fennel essential oil for the control of multi-drug resistant A. baumannii infections. However, more adequate studies must be carried out to verify the possibility of using it for fighting bacterial infections in human.]]>Aggarwal, B.B., A.B. Kunnumakkara, K.B. Harikumar, S.T. Tharakan, B. Sung and P. Anand,20087415601569Barbolla, R.E., D. Centron, A. Di-Martino, S. Maimone and C. Salgueira et al.,2003Acinetobacter baumannii strain at hospitals in Buenos Aires City.]]>45261264Baron, E.J. and S.M. Finegold,19908th Edn.,pp: 286-402, 435-438pp: 286-402, 435-438Choi, E.M. and J.K. Hwang,2004Foeniculum vulgare.]]>75557565Guardabassi, L., A. Petersen, J.E. Olsen and A. Dalsgaard,1998Acinetobacter spp. isolated from sewers receiving waste effluent from a hospital and a pharmaceutical plant.]]>6434993502Houang, E.T., Y.W. Chu, C.M. Leung, K.Y. Chu, J. Berlau, K.C. Ng and A.F. Cheng,2001Acinetobacter sp. in Hong Kong.]]>39228234Lee, S.O., NJ. Kim, S.H. Choi, T. Hyong-Kim and J.W. Chung et al.,2004Acinetobacter baumannii: A case-control study.]]>48224228Liu, S.Y., J.Y. Lin, C. Chu, L.H. Su, T.Y. Lin and C.H. Chiu,2006Acinetobacter baumannii isolated from a regional hospital in Taiwan.]]>278184Longo, B., A. Pantosti, I. Luzzi, A. Tarasi and F. Di Sora et al.,2007Acinetobacter baumannii in an intensive care unit.]]>438388Mohsenzadeh, M.,2007Staphylococcus aureus and Escherichia coli in nutrient broth medium.]]>1036933697Naas, T., P. Bogaerts, C. Bauraing, Y. Degheldre, Y. Glupczynski and P. Nordmann,2006Acinetobacter baumannii in Belgium.]]>58178182Nishio, H., M. Komatsu, N. Shibata, K. Shimakawa and N. Sueyoshi et al.,20044252565263Nordmann, P.,2004Acinetobacter baumannii, the nosocomial pathogen par excellence. ]]>52301303Ozcan, M.M., O. Sagdic and G. Ozkan,20069418421Papadopoulos, C.J., C.F. Carson, K.A. Hammer and T.V. Riley,2006Melaleuca alternifolia (tea tree) oil and components.]]>58449451Perez, F., A.M. Hujer, K.M. Hujer, B.K. Decker, P.N. Rather and R.A. Bonomo,2007Acinetobacter baumannii.]]>5134713484Quale, J., S. Bratu, D. Landman and R. Heddurshetti,2003Acinetobacter baumannii endemic in New York City.]]>37214220Ruberto, G., M.T. Baratta, S.G. Deans and H.J.D. Dorman,2000Foeniculum vulgare and Crithmum maritimum essential oils.]]>66687693Sagdic, O. and A.N.K. Yasar,2005556771Singh, B. and R.K. Kale,2008Foeniculum vulgare (Fennel) on skin and forestomach papillomagenesis, enzymes associated with xenobiotic metabolism and antioxidant status in murine model system.]]>4638423850Van Looveren, M. and H. Goossens,2004Acinetobacter sp. in Europe.]]>10684704Yu, Y.S., Q. Yang, X.W. Xu, H.S. Kong, G.Y. Xu and B.Y. Zhong,2004Acinetobacter calcoaceticus-baumannii complex in a Chinese hospital.]]>53653656