Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2008.925.929Rezaei-TaviraniMostafa ZaliHakimeh NabaiLayla ToossiParviz Malek ZadFarhad PourkhoshbakhtYousof 62008116In the present study, cytotoxicity effects of calprotectin
on Human Gingival Fibroblast (HGF) and Human Foreskin Fibroblast (HFFF)
were compared. For these evaluations, both cells were exposed to the different
concentrations of calprotectin, for 24, 48 and 72 h. Cell proliferation
was assessed using MTT assay. Our results revealed that growth inhibition
of calprotectin on HGF and HFFF occur in a dose- and time-dependent manner.
Results of this investigation showed that sensitivity of HGF cells to
cytotoxic effect of human calprotectin was more than HFFF. The results
indicate that drug resistance process is different for the two kinds of
fibroblast cells.]]>Chen, Y., Y.H. Su, C.H. Wang, J.M. Wu, J.C. Chen and S.H. Tseng,20052542034208Doljanski, F.,200447339356Ducy, P., T. Schinke and G. Karsenty,200028915011504Francis, D. and R.L. Rapid,198689271277Hande, K.R.,19983415141521Jiang, J., F.F. Nan, X.S. Yang, Y.Z. Zhang, B. Wang and B.H. Kong,200742595599Keller, G., A.V. Schally, A. Nagy, B. Baker, G. Halmos and G.B. Engel,20062815071513Martin, P.,19972767581Mikami, M., M. Kitahara, M. Kitano, Y. Ariki, Y. Mimaki, Y. Sashida, M. Yamazaki and S. Yui,199922674678Muller, G., C. Kerkhoff, J. Hankowitz, M. Pataki, E. Kovacs, K.J. Lackner and G. Schmitz,19931313171326Nakatani, Y., M. Yamazaki, W.J. Chazin and S. Yui,200524280292Poullis, A., R. Foster, M.A. Mendall and M.K. Fagerhol,200318756762Shibata, F., A. Ito, Y. Ohkuma and K. Mitsui,20052823122314Shokrgozar, M.A., H. Zali, M. Rezaei-Tavirani and S.H. Moghadamnia,2007in vitro.]]>8258263Sohnle, P.G., M.J. Hunter, B. Hahn and W.J. Chazin,200018212721275Tomonaga, M., M. Oka, F. Narasaki, M. Fukuda, R. Nakano, H. Takatani, K. Ikeda, K. Terashi, I. Matsuo, H. Soda, K.H. Cowan and S. Kohno,19968712631270Tugizov, S., J. Berline, R. Herrera, M.E. Penaranda, M. Nakagawa and J. Palefsky,20057910991112Van den Bos, C., A. Rammes, T. Vogl, R. Boynton, J. Zaia, C. Sorg and J. Roth,199813313318Wong, E.V., A.W. Schaefer, G. Landreth and V. Lemmon,199666779786Yui, S., M. Mikami and M. Yamazaki,199558650658Yui, S., Y. Nakatani, M.J. Hunter, W.J. Chazin and M. Yamazaki,200211165172Yui, S., Y. Nakatani and M. Mikami,200326753760Zali, H., S.A. Marashi, M. Rezaei-Tavirani, P. Toossi, M. Rahmati-Roodsari and M.A. Shokrgozar,20076810121015Zali, H., M. Rezaei-Tavirani, A. Kariminia, R. Yousefi and M.A. Shokrgozar,200812714