Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2008.1443.1448Ali ShabestariA.S.L. JamshidiShahram MohammadiMarjan SasaniFarhang BahadoriAli OghalaieAkbar 1120081111The aim of this study was to evaluate the prevalence of chronic
gastritis in pet dogs, to determine the histopathologic changes of gastric
mucosa and, to determine its relationship with canine gastric Helicobacter
infection. Sixty percent (n = 18), 27% (n = 8) and 13% (n = 4) of the
examined stomachs showed normal, congested and erosive gastric mucosa
respectively. Histopathologic examination was confirmed the presence of
chronic gastritis in 40% of dogs (n = 12). Lymphocytic-plasmacytic gastritis
was the most common type of chronic gastritis. Gastric Helicobacter was
detected in cytological examination of 26 out of 30 dogs (86.6%) but in
the PCR analysis, 93% of gastric samples were positive for GHLO. There
was no significant relation between the presence of Helicobacters and
chronic gastritis (p > 0.05). Follicular gastritis was detected in 12
cases (40%) and there was also no significant correlation between its
presence and GHLO`s infection (p > 0.05). In conclusion, chronic gastritis
can be considered as a prevalent disease especially in dogs. Nutritional
and environmental factors as well as individual immune response may have
role in induction of chronic gastritis, but the clinical significance
of these histopathologic changes should be evaluated.]]>Akhtardanesh, B., S.H. Jamshidi and F. Sasani,2006Helicobacter spp. infection and gastric lesions in domestic and stray cats.]]>76479488Cattoli, G., R.V. Vugt, R.G. Zanoni, R.G. Zanoni, V. Sanguinetti and R. Chiocchetti,1999Helicobacter spp. in naturally infected dogs.]]>70239250De Bock, M., A. Decostere, A. Hellemans, F. Haesebrouck and R. Ducatelle,2005Helicobacter felis and Helicobacter bizzozeronii induce gastric parietal cell loss in mongolian gerbils.]]>8503510Diker, S., R. Haziroglu, M. Akan, S. Calik and N. Kabakci,200226345351Eaton, K.A., F.E. Dewhirst, B.J. Paster, N. Tzellas and B.E. Coleman,1996Helicobacter species in dogs from random sources and pet dogs: Animal and public health implications.]]>3431653170Ettinger, S.J. and E.C. Feldman,20056th Edn.,pp: 1321-1326pp: 1321-1326Gaag, V.D. and I. N. Happe, 198953468472Guilford, W.G.,19961996pp: 451-486pp: 451-486Hanninen, M.L., I. Happonen, S. Saari and K. Jalava,1996Helicobacter bizzozeronii, a new canine gastric Helicobacter sp.]]>46160166Happonen, I., S. Saari, L. Castren, O. Tyni, M.L. Hanninen and E. Westermarck,199643305315Happonen, I., J. Linden, S. Saari, M. Karjalainen, M.L. Hanninen, K. Jalava and E. Wesermarck,199821317671774Hattori, T.,20042004Henry, A., P.H. Long, J.L. Burns and D.L. Charbonneau,198748831836Hermanns, W., K. Kregel, W. Breuer and L. Lechner,1995112307318Hwang, C.Y., H.R. Han and H.Y. Youn,20023123133Jalava, K., M. Kaartinen, M. Utriainen, I. Happonen and M.L. Hanninen,1997Helicobacter salomonis sp.nov. a canine gastric Helicobacter sp. related to Helicobacter felis and Helicobacter bizzozeronii.]]>47975982Kouri, K., R. Sayegh, C. Yaghi, K. Honien and E. Gereon et al.,200250149156Lavelle, J.P., S. Landas, F.A. Mitros and L.L. Conklin,199439744750Lecoindre, P., M. Chevallier, S. Peyrol and M. Boude,1995146671680Lee, A.,1989Campylobacter pylori and Clo in Animals: Overview of Mucus-Colonizing Organisms.]]>1989pp: 246-260pp: 246-260Otto, G., J. Hazell, G. Fox, C. R. Howlett, J.C. Murphy, J.L. O’Rourke and A. Lee,19943210431049Redeen, S., F. Petersson, K.A. Jonsson and K. Borch,2003Helicobacter pylori infection in a general population sample.]]>35946950Robic, M., B.B. Artokovic and A. Beck,200777103111Simpson, K.W., P. McDonough and D. Strauss Ayali,1999Helicobacter felis infection in dogs: Effect on gastric structure and function.]]>36237246Simpson, K.W., D. Strauss-Ayali and E. Scanziani,2000Helicobacter felis infection is associated with lymphoid follicular hyperplasia and mild gastritis but normal gastric secretory function in cats.]]>68779790Strauss-Ayali, D. and K.W. Simpson,199929397414Yamasaki, K., H. Suematsu and T. Takahashi,1998212529533