Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2007.3175.3179EbrahimiM. ShamabadiN. 1220071018Recent studies have shown that certain man-made compounds (including some pesticides and herbicide) through interfering with endocrine system, have the capability to induce developmental and reproductive abnormalities in humans and animals. Pesticides are currently being used in large scales in many developed and developing countries (including Iran), so this study has been conducted to determine the percentage of endocrine disruptor agents in pesticides used in Fars province. The results showed that more than 1,581,690 L of pesticides, in 86 different brands, have been used in Fars province during year 1380 and 25.93% (34 types) of them had at least one carcinogenic agents. At least 30 pesticides (711720 L, 44.99%) had one endocrine disruptor agent and therefore can be classified as environmental hormones or endocrine disrupting chemicals. The percentage of pesticides whom interfering with normal endocrine system activity were, 7.82% (66572 L), 4.54% (39975 L), 22.02% (348400 L), 5.12% (81000 L) and 21.18% (34500 L) of pesticides were antiestrogenic, antiandorgenic, antityroidic, antigonadotropin and anitestroid hormones, respectively. The results showed that about 50% of pesticides which currently being used in Fars province should be banned.]]>Akingbemi, B.T., R.S. Ge, G.R. Klinefelter, G.L. Gunsalus and M.P. Hardy,200062571578Akingbemi, B.T. and M.P. Hardy,200133391403Alberts, S.C., R.M. Sapolsky and J. Altmann,199226167178Birrell, S.N., L.M. Butler, J.M. Harris, G. Buchanan and W.D. Tilley,20072007Bolt, H.M. and G.H. Degen,200276187193Bretveld, R., M. Brouwers, I. Ebisch and N. Roeleveld,2007331328Buranatrevedh, S. and D. Roy,2001641729Calle, E.E., H. Frumkin, S.J. Henley, D.A. Savitz and M.J. Thun,200252301309Charlier, C. and G. Plomteux,2002127Charlier, C., A. Albert, P. Herman, E. Hamoir, U. Gaspard, M. Meurisse and G. Plomteux,200360348351Cohn, B.A., P.M. Cirillo, M.S. Wolff, P.J. Schwingl and R.D. Cohen et al.,200336122052206Correa-Reyes, G., M.T. Viana, F.J. Marquez-Rocha, A.F. Licea, E. Ponce and R. Vazquez-Duhalt,20072007Dickerson, R.L., C.S. McMurry, E.E. Smith, M.D. Taylor, S.A. Nowell and L.T. Frame,199923397108Forawi, H.A., P.B. Tchounwou and R.W. McMurray,200419113Gish, C.D.,19703241252Gotz, F., S. Thieme and G. Dorner,2001394043Gray, L.E. Jr.,1998102-103331335Guillette, L.J., Jr.,2006114912Guillette, L.J. and B.C. Moore,200624134141Hinck, J.E., V.S. Blazer, N.D. Denslow, K.R. Echols and T.S. Gross et al.,2007378376402Holmes, P., P. Rumsby and P.T. Harrison,2004105459Jaga, K. and H. Duvvi,2001121107113Jin, B., L. Turner, Z. Zhou, E.L. Zhou and D.J. Handelsman,19998436133619Kamath, S.K., G. Murillo, R.T. Chatterton, Jr. E.A. Hussain and D. Amin et al.,1999351626Lemaire, G., B. Terouanne, P. Mauvais, S. Michel and R. Rahmani,2004in vitro.]]>196235246Lind, P.M., M.R. Milnes, R. Lundberg, D. Bermudez, J.A. Orberg and L.J. Guillette Jr.,2004112359362Liney, K.E., J.A. Hagger, C.R. Tyler, M.H. Depledge, T.S. Galloway and S. Jobling,20061148189Lorenzen, A., W.L. Casley and T.W. Moon,2001176169180Mansour, S.A.,200419891115Markey, C.M., M.A. Coombs, C. Sonnenschein and A.M. Soto,200356775Martin, S.A., Jr., S.D. Harlow, M.F. Sowers, M.P. Longnecker, D. Garabrant, D.L. Shore and D.P. Sandler,200213454458Nhan, D.D., F.P. Carvalho, N.M. Am, N.Q. Tuan, N.T. Yen, J.P. Villeneuve and C. Cattini,2001112311320Ohyama, K.,200462379384Rattner, B.A., V.P. Eroschenko, G.A. Fox, D.M. Fry and J. Gorsline,1984232683689Recchia, A.G., A. Vivacqua, S. Gabriele, A. Carpino, G. Fasanella, V. Rago, D. Bonofiglio and M. Maggiolini,200421134144Rooney, A.A., D.A. Crain, A.R. Woodward and L.J. Guillette, Jr.,20041352534Rudel, R.A., D.E. Camann, J.D. Spengler, L.R. Korn and J.G. Brody,20033745434553Shinomiya, N. and M. Shinomiya,2003137175183Singleton, D.W. and S.A. Khan,20038s110s118Snedeker, S.M.,20011093547Steinhardt, G.F.,2004545203215Stevens, J.T., A. Tobia, J.C.T. Lamb, C. Tellone and F. O'Neal,199750415431Tapiero, H., G.N. Ba and K.D. Tew,2002563644Tsuda, H., A. Naito, C.K. Kim, K. Fukamachi, H. Nomoto and M.A. Moore,2003In vivo experimental and epidemiological findings.]]>33259270Turusov, V., V. Rakitsky and L. Tomatis,2002110125128Veeramachaneni, D.N.,200060-61121130Weltje, L., F.S. vom Saal and J. Oehlmann,200524431437Whitehead, S.A. and S. Rice,2006204561Witorsch, R.J.,200240905912Bretveld, R.W., C.M.G. Thomas, P.T.J. Scheepers, G.A. Zielhuis and N. Roeleveld,20062006Gupta, P.K.,20041988390