Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2006.2261.2266Ipomoea turpethum]]>Harun-Or-RashidMd. KarimNurul GafurM. A.SadikMd. GolamAnisuzzamanA.S. M.SugimotoNoaki AzamA.T.M. Zafrul122006912Extensive chromatographic separation and purification of the organic solvent extracts of stem of I. turpethum afforded three compounds, N-p-coumaryl tyramine (EH4), daucosterol (CH1) and 2-hydroxybenzoic acid (CH2); first isolated from this plant. The structures of these compounds were determined by spectroscopic analysis, including 1H- and 13C-NMR, as well as by UV, IR and electrospray ionization mass spectrometry (ESI-MS). On screening against pathogenic bacteria and fungi; compounds CH2 and EH4 as well as extracts showed significant antibacterial and antifungal activity. The Minimum Inhibitory Concentration (MIC) against Bacillus subtilis and Shigella dysenteriae of compounds CH2 and EH4 were 64 μg mL-1. On in vivo cytotoxicity studies against brine shrimp; compounds CH2 and EH4 showed LC50 (Leathal concentration for 50% mortality) values 54.03 and 43.41 μg mL-1, respectively.]]>Alam, S., 2004116325331Bauer, A.W., W.M.M. Kirby, J.C. Sherris and M. Turck,196645493496Gafur, M.A., T. Obata, F. Kiuchi and Y. Tsuda, 199745620625Goodman, L.S., A.G. Gilmann and A. Gilmann,19806th Edn.,pp: 1299-1313pp: 1299-1313Guan, Y., T.W. Miao Lin and J. Ye, 2006Ipomoea batatas by capillary electrophoresis with electrochemical detection. ]]>542428Khan, M.M.A.A., 1992Ipomoea turpethum and Scilla indica. ]]>997173Khelfi, T.F., R.A. Taha, O.A. Badary, A. Lezzar and F.M.A. Hamada, 200317324328Kojima, H., N. Sato, A. Hantano and H. Ogura, 1990Prunella vulgaris.]]>2923512355Masako, A.B.E., Y. Ozawa, Y. Uda, F. Yamada, Y. Morimitsu, Y. Nakamura and T. Osawa, 20046816011604McLaughlin, J.L. and J.E. Anderson,1988Rahman, A.T., M.K. Bhatti, F. Akter and M.I. Choudhury, 1992Fumaria indica.]]>3128692872Rahman, A.A., A.T.M.Z. Azam and M.A. Gafur, 2000Clerodendrum indicum. ]]>1716Haque, M., M.O. Ullah and K. Nahar,2009In vitro Antibacterial and Cytotoxic Activities of Different Parts of Plant Swietenia mahagony.]]>12599602Rashwan, O.A., 200277580Sahabuddin,1999Operculina turpethum L. ]]>8157163Saieed, P., R.M. Reza, D. Abbas, R. Seyyedali and H. Aliasghar,2006Ruta graveolens L. extract on guinea pig liver aldehyde oxidase.]]>54913Schimming, T., S.K. Jenett, K. Siems, L. Witte and E. Eich,2005Ipomoea nil. ]]>60958959Spasova, M., K.V. Kortenska, I. Totseva, G. Ivanova, L. Georgiev and T. Milkova, 200512369375Zhao, G., Y. Hui, J.K. Rupprecht, J.L. McLaughlin and K.V. Wood,1992Asimina triloba.]]>55347356Kirtikar, K.R. and D.B. Basu,1994Nasar, E.L.S.M.M., 1982Convolvulus lantus and C. arvensis. ]]>53189191Reiner, R.,1982pp: 39-98pp: 39-98Budavari, S.M., J. O’Neil, A. Smith and P.E. Heckleman,198911th Edn.,Srivastava, O.P.,19841984pp: 72-79pp: 72-79Rashid, M.H.O., M.A. Gafur, M.G. Sadik and A.A. Rahman,2002Ipomoea turpethum.]]>5597600