Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2006.1338.1341MohsenShahtaheri Seyed7200697The study of micro architecture of cancellous bone is important factor in diagnosis of bone diseases such as osteoporosis. Bone mineral density depends on factors like sex, age, genetic and environment. Bone mass, number of trabeculae, trabecular thickness decrease with aging in both sexes. The aim of this study was to investigate trabecular bone architecture in young healthy men and women. Iliac crest bone biopsies were taken from 53 healthy Caucasian men and women (28 men and 28 women, ages 20-49). The histomorphometry of cancellous bone was compared in undecalcified sections of iliac crest bone biopsies. Sections (8 μm) were analyzed by an automated trabecular analysis system (TAS) which measures a comprehensive range of structural variables such as bone volume, trabecular separation, number, connectivity and width. Although variables like bone volume, bone surface and trabecular thickness in men were more than women but this difference was not significant. Trabecular separation in men was less than women and this was significant. In addition number of trabecular nodes and index of node to terminus in men was more than women which this difference was not significant. Trabecular length was more in men than women and this was significant. In conclusion despite no significant difference in some of the above variables there is more mechanical strength due to less separation and more trabecular length in trabecular bone architecture in young men in comparison with young women.]]>Aaron, J.E., N.B. Makins and K. Sagreiya,19872152671Genants, H.K., C.E. Cann and B. Ettinger,198297699705Henry, Y.M., D. Fatayerji and R. Eastell,200415263273Kleerekoper, M. and A.R. Villanueva,198537594597Lu, P.W., C.T. Cowell and S.A.L. Jones,20008113321339Mazess, R.B., 1982165239252Mosekilde, L.,1990116773Mundy, G.R.,1994367216217Mundy, G.R.,19955176179Parfitt, A.M., C.H.E. Mathews and A.R. Villanueva,19837213961409Riggs, B.L., H.W. Wahner and W.L. Dunn,198167328335Riggs, B.L., H.W. Wahner and L.J. Melton,19867714831491Saino, H., D.H. Carter, A.J. Natali, S.M. Shahtaheri and J.E. Aaron,200332660668Seeman, E.,200235918411850Shahtaheri, S.M., J.E. Aaron, D.R. Johnson and S. K. Paxton,1999194407421Smith, D.M., M.R.A. Khairi and C.C. Jr. Johnston,197556311318Thomsen, J.S., E.N., Ebbesen and L. Mosekile,200130267274Vanderschueren, D., S.B., Vandenput, S. Boonen and M.K. Lindberg, R. Bouuillon and C. Ohlsson,200425389425