Journal of Pharmacology and Toxicology1816-496x2152-100xAcademic Journals Inc.10.3923/jpt.2007.496.501Allium cepa, Allium sativum or Sodium Selenite in Wistar Rats]]>GadirE.H. AbdelGadirW.S. AbdelI. AdamS.E. 5200725Although diets containing mixtures of 600 mg kg-1 of KBrO3 plus 2% Allium sativum, 600 mg kg-1 KBrO3 plus 2% Allium cepa and 600 mg kg-1 of KBrO3 plus 1 mg kg-1 sodium selenite did not adversely affect the growth of Wistar rats, a significant decrease in body weight gain, hepatonephropathy, desquamation of the intestinal epithelium into the lumen and lymphocytic accumulation in vital organs were observed in the rats fed a diet consisting of 600 mg kg-1 of KBrO3 singly for 4 weeks. These changes associated with macrocytic normochromic anemia were correlated with alterations in serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) activities and concentrations of cholesterol, urea and other serum constituents. However, none of the rats died during the 4-week period.]]>Abdel Gadir, E.H., W.S. Abdel Gadir and S.E.I. Adam,2006Allium cepa, Allium sativum and sodium selenite.]]>1284288 Combs, GF. Jr., L.C. Clark and B.W. Turnbull,199710227234Corrals, X., M. Guerra, M. Granito and J. Ferris,199343234240Corvilain, B., B. Contemper, A.O. Longombe, P. Goyens and C. Gerry-Decoster et al.,19935724452485Dafalla, R.,19851985Fenwick, G.R., A.B. Hanley and J.R. Whitaker,1985Allium: Part 3.]]>23173Huff, W.E., J.A. Doerr, C.J. Wabeck, G.W. Chaloupha, J.D. May and J.W. Merkley,19836217641771Khan, N., S. Sharma and S. Sultana,2003Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: Diminution of oxidative stress.]]>22193203Kurokawa, Y., S. Aoki, Y. Matsushima, N. Takamura, T. Imazawa and Y. Hayashi,198677977982Kurokawa, Y., A. Mackawa, N. Takahashi and Y. Hayeshi,199087309355Ozer, N.K., K.D. Boscoboini and A. Azzi,199535117124Reuter, H.D.,1995Allium sativum and A. ursinum. Part 2.]]>25163Sai, K., M. Hayashi, A. Takagi, R. Hasegaura, T. Sofuni and Y. Kurokawa,1992269113118Schalm, O.W., N.C. Jain and G.H. Carroll, 19753rd Edn.,Pages: 807Pages: 807Snedecor, G.W. and W.G. Cochran,19898th Edn.,Pages: 524Pages: 524Umemura, T., K. Sai, A. Takagi, R. Hasegawa and Y. Kurokawa,199516593597