Journal of Pharmacology and Toxicology1816-496x2152-100xAcademic Journals Inc.10.3923/jpt.2007.264.270H)-oxazolones Having Antimicrobial Activity]]>PashaM.A. JayashankaraV.P. VenugopalaK.N. RaoGopal Krishna 3200723A straightforward and a general method has been developed for the synthesis of some important functionalized 4-arylmethylidene-2-phenyl-5(4H)-oxazolone derivatives by combining araldehydes and hippuric acid in the presence of catalytic amount of zinc oxide at room temperature in ethyl alcohol is reported. The method was very easy, rapid and products obtained were in excellent yields. The compounds were purified, characterized and were subjected for in vitro antibacterial activity (determination of Minimum Inhibitory Concentration (MIC)by micro titration method) using two standard drugs Streptomycin and Ampicillin against Bacillus subtilis and Escherichia coli. Five of the synthesized compounds showed remarkable antibacterial activity when compared to that of standards.]]>Avenoza, A., J.H. Busto, C. Cativiela and J.M. Peregrins,2002H)-oxazolones: [4+2] cycloaddition versus [4+3] cycloaddition/ nucleophilic trapping.]]>4341674170Bautista, F.M., J.M. Campelo, D.L. Garcia and J.M. Marinas,199228795Bautista, F.M., J.M. Campelo, A. Garcia, D. Luna, J.M. Marinas and A.A. Romero,20022227234Bunnel, E., C. Cativiela and M.D. Diaz de Villegas,19955189238934Cannella, R., F. Clerici, M.L. Gelmi, M. Penso and D. Pocar,1996H)-oxazolones.]]>6118541856Cativiela, C. and E. Melendez,1978H)-oxazolones.]]>1832834Cativiela, C., J.M. Fraile, J.J. Garcia, M.P. Lopez, J.A. Mayoral and E. Pires,1996H)-oxazolone with heterogeneous catalysts.]]>723912398Cativiela, C., M.D. Daz de Villegas, J.I. Garca and A.I. Jimenez,19975344794486Cativiela, C., M.D. Diaz-de-villegas and J.A. Galvez,19994010271030Cavalier, F. and J. Verducci,19953644254428Croce, P.D., R. Ferraccioli and C.L. Rosa,1994124992502Donati, D., A.G. Aburbeh, B. Natalini, C. Marchioro and R. Pellicciari,19965299019908Lowdin, E., I. Odenholt-Tornqvist, S. Bengtsson and O. Cars,19933722002205Gelmi, M.L., F. Clerici and A. Melis,1997H)-Oxazolones. Part X. acid and base effects on the translactonization reaction of 4-(2-oxa-alkylidene)-5(4H)-oxazolones: New synthesis of 5-alkylidene-3-benzoylamino-2(5H)-furanones.]]>5318431854Gottwald, K. and D. Seebach,199955723738Hamidian, H. and A.M. Tikari,2006H)-oxazolone derivatives with using palladium (II) acetate as a catalyst and microwave irradiation in solvent free condition.]]>192930Karade, N.N., S.G. Shirodkar, B.M. Dhoot and P.B. Waghmare,2005H)-oxazolones.]]>14647Khodaei, M.M., A.R. Khosropour and S.J.H. Jomor,200310638641Kojima, S., H. Ohkawa, T. Hirano, S. Maki, H. Niwa, M. Ohashi, S. Inouye and F.I. Tsuji,1998Aequorea green fluorescent protein (GEP).]]>3952395242Kotretsou, S., M.P.M. Leclerey, V. Kokotou, R. Brasseur, M.P. Geogiadis and P.M. Tulkens,19953847104713Martinez, A.P., W.W. Lee and L. Goodman,19642027632771Meiwes, J., M. Schudock and G. Kretzschmar,19978527536Mesaik, M.A., S. Rahat, K.M. Khan, M.I. Choudhary and M. Shahnaz et al.,20041220492057Pasha, M.A., K. Manjula and V.P. Jayashankara,200636321324Pasha, M.A. and V.P. Jayashankara,20064X (X = Cl, Br, I) in methanol under ultrasonic conditions.]]>134246Pasha, M.A. and V.P. Jayashankara,20061573578Pasha, M.A. and V.P. Jayashankara,20062-Catalyzed tandem reaction: Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones from β-keto ester, substituted aldehydes and urea/thiourea using microwaves under solvent free condition.]]>126166Pasha, M.A. and V.P. Jayashankara,20063617871793Pasha, M.A. and V.P. Jayashankara,2006p-TSA) catalyzed efficient synthesis of bis(indolyl)methanes under grindstone method.]]>1585590Pasha, M.A. and V.P. Jayashankara,20066810171023Paul, S., P. Nanda, R. Gupta and A. Loupy,2004H)-oxazolones under solvent-free conditions.]]>45425427Penalba, J., R. Puchades, A. Maquieira, S. Gee and B.D. Hammock,20001599106Rao, P.S. and R.V. Venkataraman,1994H)-oxazolones.]]>33B984985Ringold, H.J., B. Loeken, G. Rosenkranz and F. Sondheimer,195678816819Seebach, D., G. Jaeschke, K. Gottwald, K. Matsuda, R. Formisano and D.A. Chaplin,19975375397556