Journal of Pharmacy and Allied Health Sciences2224-2503Asian Network for Scientific Information10.3923/jpahs.2012.40.46Cassia alata ]]>AlalorC.A. IgwiloC.I. JerohE. 2201222The antibacterial activity of the aqueous and methanol extracts of sundried leaves of Cassia alata was investigated by testing the extracts against some pathogenic Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa using the Agar cup plate method. The Minimum Inhibitory Concentration (MIC) of the aqueous extract against susceptible test organism was determined using the Agar dilution method. The results showed that the plant part can be used to treat infections caused by S. aureus and B. Subtilis which were susceptible. The in vitro findings justify the use of the extract of Cassia alata in traditional medicine practice for the treatment of some external skin infections. Cassia alata has shown to be a very versatile plant and can be a viable alternative as an antibacterial agent in the future either alone or in combination with other medicinal plants, if formulated into appropriate pharmaceutical dosage forms. Further, scope exists for in vivo research studies with preformulation testing, pharmaceutical dosage formulation and development, pharmacokinetics, safety and efficacy in patients.]]>Abubacker, M.N., R. Ramanathan and T.S. Kumar,2008In vitro antifungal activity of Cassia alata Linn. flower extract.]]>769Ajose, F.O.A.,2007464855Awal, M.A., A. Nahar, M.S. Hossain, M.A. Bari, M. Rahman and M.E. Haque,2004Cassia alata Linn. and their antibacterial potency.]]>4188193Chukeatirote, E., P. Hanpattanakit, A. Kaprom and J. Tovaranonte,2007Senna spectabilis and S. tora.]]>2123126El-Mahmood, A.M. and J.H. Doughari,2008Cassia alata Linn.]]>2124129Elujoba, A.A., O.O. Ajulo and G.O. Iweibo,1989Cassia species for laxative activity.]]>714531457Esimone, C.O., C.S. Nworu, U.S. Ekong and B. Okereke,2008Cassia alata-based herbal soap.]]>2008Fernand, V.E., D.T. Dinh, S.J. Washington, S.O. Fakayode, J.N. Losso, R.O. van Ravenswaay and I.M. Warner,2008Cassia alata L. by use of high performance liquid chromatography.]]>74896902Idu, M., S.E. Omonigho and C.L. Igeleke,2007Senna alata L. flower.]]>10806809Krishnan, N., S. Ramanathan, S. Sasidharan, V. Murugaiyah and S.M. Mansor,2010Cassia spectabilis leaf extracts.]]>6510514Obeidat, M., M. Shatnawi, M. Al-Alawi, E. Al-Zu'bi and H. Al-Dmoor et al.,201275967Moriyama, H., T. Iizuka and M. Nagai,2001Cassia alata leaves and its structural elucidation.]]>121817820Odunbaku, O.A. and O.A.F. Lusanya,2011Senna alata and antimicrobial drugs on some pathogenic microbes.]]>521622165Oladunmoye, M.K., F.C. Adetuyi and F.A. Akinyosoye,2007Cassia hirsuta (L.) extract on DNA profile of some microorganisms.]]>2142146Palanichamy, S. and S. Nagarajan,1990Cassia alata leaf extract.]]>29337340Pieme, C.A., V.N. Penlap, B. Nkegoum, C.L. Taziebou, E.M. Tekwu, F.X. Etoa and J. Ngongang,2006Senna alata (L.) Roxb (Ceasalpiniaceae).]]>5283289Pieme, C.A., J.P. Dzoyem, F.A. Kechia, F.X. Etoa and V. Penlap,2008In vitro antimicrobial activity of extracts from some Cameroonian medicinal plants.]]>8902907Reezal, I., M.N. Somchit and M.A. Rahim,2002In vitro antifungal properties of Cassia alata (Gelenggang Besar).]]>2002pp: 654659Roy, J., D.M. Shakleya, P.S. Callery and J.G. Thomas,2006317Uddin, S.N., M.E. Ali and M.N. Yesmin,2008Senna tora Roxb.]]>396100Sharma, S., M.S. Dangi, S. Wadhwa, V. Daniel and A. Tiwari,2010Cassia tora leaves.]]>18486Villasenor, I.M., A.P. Canlas, M.P.I. Pascua, M.N. Sabando and L.A.P. Soliven,2002Cassia alata Linn. leaf extracts.]]>169396