Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2013.797.802El-MazahiMohamed Mohamed Ashmawy SakrMagdy Mohamed El-KhaleegyHany Abd El-Hady El-NagarMahfauze Awad 82013138Presence of BCG scar is used as an indicator of vaccination but its significance is still the subject of controversy. The aim of the study was evaluate the immunogenicity of neonatal BCG vaccination in children age 6 years to detect if a booster dose is necessary or not. Two hundred children, selected from primary schools in Damietta by stratified random sampling, from March to December 2010. They divided into two groups, study group (150) with BCG scar, second group (50) lack BCG scar. A questionnaire including personal data, vaccination, disease and drug intake history was completed. Then BCG scar was checked and measured in mm and PPD test was done. Examination for anemia, jaundice, organomegaly and assessment of nutritional status was done. Male to female ratio of 1.27: 1; no significant difference between both groups as regard anthropometric measurement while there was significant increase in BCG diameter in study in comparison to control group (4.66±1.88 vs. 0.0±0.0 mm, respectively). PPD test results revealed that 182 (91.0%) were non-reactive while 18 (9.0%) were suspicious and there was significant difference between groups. Finally, there was powerful, positive, significant correlation between BCG scar and PPD test results. Conclusion of this study revealed that children at the age of school entry better to receive booster dose of BCG vaccination to lengthen and increase the efficacy of the immunity.]]>Al-Kassimi, F.A., A.K. Abdullah, I.O. Al-Orainey and A.B. Benar, 199172101104Aronson, N.E., M. Santosham, G.W. Comstock, R.S. Howard, L.H. Moulton, E.R. Rhoades and L.H. Harrison, 200429120862091Ballew, K.A. and D.M. Becker,19958810251030Barreto, M.L., S.M. Pereira and A.A. Ferreira,200682S45S54Briassoulis, G., I. Karabatsou, V. Gogoglou and A. Tsorva, 2005311Colditz, G.A., T.F. Brewer, C.S. Berkey, E. Wilson, E. Burdick, H.V. Fineberg and F. Mosteller,1994271698702Ildirim, I., M. Hacimustafaoglu and B. Ediz, 19951410601063Konstantinos, A.,2010331218Leung, C.C., W.W. Yew, C.M. Tam, C.K. Chan and K.C. Chang et al., 200560124129Menzies, R. and B. Vissandjee, 1992145621625Miret-Cuadras, P., J.M. Pina-Gutierrez and S. Juncosa, 1996775258Rowland, K., R. Guthmann, B. Jamieson and D. Malloy, 200655718720Centers for Disease Control and Prevention (CDC), 199746846851Sakha, K. and M. Aghaee, 2003253438Sakha, K. and A.G. Behbahan,200811930933Scholten, J.N., P.I. Fujiwara and T.R. Frieden, 199933141WHO,19981998