Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2008.85.89NouriM. PipelzadehM.H. BadieiA. 1200881In this study, the effectiveness of standardised garlic tablets (Kwai)
was compared with clofibrate in the treatment of hyperlipidaemia. A total
of 20 patients with total cholesterol and triglyceride values above 200
and 280 mg dL-1, respectively, voluntarily took part in this
study. Patients were randomly allocated to take a total of nine 100 mg
standardised garlic tablets daily in three divided doses, or two capsules
of 500 mg clofibrate a day at 12 h intervals. The serum triglyceride and
cholesterol were measured on weeks 4 and 8 of treatment. The results showed
that garlic tablets were superior to clofibrate in reducing the extent
and the rate of both triglyceride and cholesterol levels. Garlic tablets
and clofibrate capsules reduced the total cholesterol levels by an average
of 9.8, 17.5, 3 and 7.2%, respectively after 4 and 8 weeks. While the
triglyceride levels were reduced by 34.8 and 43.7% in the garlic-treatment
group compared with 21.3 and 25.5% in the clofibrate-treated group for
the corresponding periods. The safer profile associated with garlic tablets
suggests that this natural source is a better alternative to clofibrate
in the treatment of hyperlipidaemia.]]>Banerjee, S.K. and S.K. Maulik,20022002Cavallito, C.J. and J.H. Bailey,1944Allium sativum. I. Isolation, physical properties and antibacterial action.]]>6619501951Chi, M.S.,1982171174178Chi, M.S., E.T. Koh and T.J. Stewart,1982112241248Gardner, C.D., L.D. Lawson, E. Block, L.M. Chatterjee, A. Kiazand, R.R. Balise and H.C. Kremer,2007167346353Holzgartner, H., U. Schmidt and U. Kuhun,19924214731477Inuzuka, S., N. Tomiyasu, M. Kumamoto, T. Egashira, J. Kinoshita, S. Shishido, M. Sata and T. Ueno,2003507780Kojuri, J., A.R. Vosoughi and M. Akrami, 20072007Lawson, D.D.,19981998pp: 176-209pp: 176-209Li, M., J.R. Ciu, Y. Ye, J.M. Min, L.H. Zhang, H. Wang, Gares, J. Cros, M. Wright and J. Leung-Tack,200223573579Neil, H.A., C.A. Silagy, T. Lancaster, J. Hodgeman, K. Vos and J.V.V. Moore,199630329334Qureshi, A.A., N. Abuirmeileh, Z.Z. Din, C.E. Elson and W.C. Burger,198318343348Qureshi, A.A., Z.Z. Din, N. Abuirmeileh, W.C. Burger, Y. Ahmad and C.E. Elson,198311317461755Qureshi, A.A., T.D. Crenshaw, N. Abuiremeileh, D.M. Peterson and C.E. Elson,198764109115Rivlin, R.S.,2001131951S954SSilagy, C. and A. Neil,19941994pp: 39-45pp: 39-45Stevinson, C., M.H. Pittler and E. Ernst,200019420429Tattelman, E., 200572103106Warshafsky, S., R.S. Kamer and S.L. Sivak,1993119599605Yeh, Y.Y. and S.M. Yeh,199429189193