Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2008.491.497K.B.A. OwireduWilliam K.D. EphraimRichard AmiduN. Eghan JnrB.A. QuayeL. 5200885This study specifically evaluate the predictive performance
and accuracy of the six renal function equations in patients presenting
with CKD in our community. The results of these predictive equations for
50 patients using stage of CKD and/or with serum creatinine >200 μmol
L^{-1} were compared with the recommended methods (4v-MDRD and
CG). Another 55 subjects with similar age group and sex distributions
but without kidney pathology were studied as control. The most accurate
results were obtained with the reference equations (4v-MDRD and CG) with
CG having a slight edge over 4v-MDRD equation. The sensitivity and specificity
of the 4v-MDRD equation to detect Glomerular Filtration Rate (GFR) values
< 60 mL/min/1.73 m^{2 }were 67.3 and 63.9%, respectively; that
of CG was 62.9 and 71.3%, respectively. These results suggest that measurement
of GFR with predictive equations might be a prudent strategy for the assessment
of renal function among the CKD population.]]>Bland, J.M. and D.G. Altman,1986Cockcroft, D.W. and M.H. Gault,1976Coresh, J., G, Eknoyan and A.S. Levey,2002Du Bois, D. and E.F. Du Bois,1989Fontsere, N., I. Salinas, J. Bonal, B. Bayes, J. Riba, F. Torres,J. Rios, A. Sanmarti and R. Romero,2006Gates, G.F.,1985Guignard, J.P., A. Torrado, H. Feldman and E Gautier,1980Herget-Rosenthal, S., A. Bokenkamp and W. Hofmann,2007Jelliffe, R.W. and S.M Jelliffe,1972Levey, A.S.,1990Levey, A.S., R. Atkins, J. Coresh, E.P. Cohen, A.J. Collins and K.U. Eckardt et al.,2007Levey, A.S., J.P. Bosch, J.B. Lewis, T. Greene, N. Rogers and D. Roth,1999Levey, A.S., J. Coresh, E. Balk, A.T. Kausz and A. Levin et al.,2003Levey, A.S., T. Greene, G.J. Beck, A.W. Caggiula, J.W. Kusek, L.G. Hunsicker and S. Klahr,1999National Kidney Foundation,2002Ocheke, I.E. and E.I. Agaba,2006Perrone, R.D., N.E. Madias and A.S. Levey,1992Schwartz, G.J., G.B. Haycock, C.M. Jr. Edelmann and A. Spitzer,1976