Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2006.666.669KhamehchianT. SharifiH. MazuchiT. TalariS.A. 4200664This descriptive study was done duo to determine of frequencies of precancerous lesions and its significance in gastric cancer prophylaxis and no accessible data about their in this region. From 177 patients with gastrointestinal symptoms that were selected for endoscopy, biopsies were taken from fundus, antrum, lesser curvature. 24.9% of patients had precancerous lesion that 20.9% were Intestinal metaplasia (IM) and 4% of them were dysplasia. Fifty four percent of IM was in antrum, 27.1% in fundus and 18.9% in lesser curvature. In patients with precancerous lesions the most clinical symptom was abdominal pain (29.5%) and the least common was melena (9.1%) and 52.8% of them had Helicobacter pylori (HP) infection. 39.4% of patients were female and 63.3% were male. The most common precancerous lesions were observed in the fourth decade life (29.5%) Therefore considering to high frequency of precancerous lesions in this study and its significance in gastric cancer prophylaxis, serial endoscopic studies are recommended.]]>Abdel Wahab, M.,1998431320Conchillo, J.M., G. Houben, A. Bruiine and R. Stockbrugger,200110307312Edit, S. and W. Stolten,199530192192Eurensel, T. and M. Ozyardimcic,199615215219Ikukokato, J., V.M. Plummer and G. Lopez et al.,2004Helicobatcer pylori related gastric precancerous lesions in venzuela.]]>13468476Munoz, N., I. Kato, S. Peraza, G. Lopez and E. Carrillo et al.,199654146Mutoh, H., S. Sakurai, K. Satoh, H. Osawa, Y. Hakamata, T. Takeuchi and K. Sugano,20045314161423Ohkuma, K., M. Okada, H. Murayama, M. Seo, K. Maeda, M. Kanda and N. Okabe,2000Helicobacter pylori infection with atrophic gastritis and intestinal metaplasia.]]>1511051112Rubio, C.A. and J. Jessuruny,199283491494Sat Arkar, R.P., P. Sawant, S. Nanivadekar and C. Shroff,1977Helicobacter pylori and intestinal metaplasia of gastric mucosa.]]>161617Shoushan, S., E.L. Sherif and A.E. Guneid,1993Helicobacter pylori and intestinal metaplasia, comparison between British and Yemeni patients.]]>8813731376Tadataka, Y., C. Owyang and D.W. Powell,20034th Edn.,pp: 1417pp: 1417Thomas, G., S. Morale, E. Richard, M. Sampliner and A. Bhattachayya,199792414418Wang, C.,1998Helicobacter pylori infection and age the development intestinal metaplasia. A multiple logitic regression analysis.]]>45223227Wei, C., Y. Lianzhang, M.H. Gail, J.M. Yun and S. William et al.,199827941944You, W.C.,199827945948