Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2006.1029.1032MarjaniAbdoljalal 6200666In this study the plasma level of zinc and Magnesium were determined in 50 type 2 diabetic patients and 50 healthy people. The sampling of type 2 diabetic patients were randomized. Diabetic patients studied were without any complications. Samples were analyzed using Randox kit with Spectrophotometric method. The plasma zinc (116.78±5.51 μg dL-1) and Magnesium (1.55±0.12 meq L-1) levels significantly decreased in type 2 diabetic patients (p<0.001) when compared with control groups (146.86±9.06 μg dL-1, 1.84±0.10 meq L-1, respectively). It is concluded that type 2 diabetes mellitus can result in changes in Zinc and Magnesium levels. The decreased plasma Zn and Mg that we demonstrated in this study in patients with type 2 diabetes mellitus probably reduce insulin sensitivity and may increase risk of secondary complications, it maybe prudent in clinical practice to periodically monitor plasma Zn and Mg concentrations in type 2 diabetic patients. If plasma Zn and Mg were decreased, an intervention to increase of dietary intake of Zn and Mg may be beneficial for these patients.]]>Barham, D. and P. Trinder,197297142145Boer, G.S., R.R. Little, N. Garrett, W. Brown, D.E. Goldstein and M.H. Nahm,19923824142418Brown, I.R., A.M. McBain, J. Chalmers, I.W. Campbell, E.R. Brown and M.J. Lewis,1999283119128De Valk, H.W.,199954139146Durlach, J. and Y. Rayssiguier,19832192224El-Yazigi, A., N. Hannan and D.A. Raines,199118129134Yazigi, A., N. Hannan and D.A. Raines,1993226775Evliaoglu, O., N. Kilicaslan, N. Uzuncan, B. Karaca, A. Kocaclebi, N. Yensel and S. Inci,20022002pp: 285286Franz, M.J. and J.P. Bantle,1999Fujii, S., T. Takemura, M. Wada, T. Akai and K. Okuda,198214161162Homster, R. and B. Zak,19853113101313Johnnson, G., B.G. Danielson, S. Ljunghall and L. Wibell,19822178180Kannel, W.B. and D.L. McGee,197924120352038Kinlaw, W.B., A.S. Levine, J.E. Morley, S.E. Silvis and C.J. McClain,198375273277Lamb, C.A., O.G. Bentley and J.M. Beattle,19581958pp: 113McNair, P., M.S. Christensen, C. Christiansen, S. Madsbad and I. Transbol,1982128185Mocchegianai, E., M. Boemi, P. Fumelli and N. Fabris,198938932937Roffi, M., C. Kanaka, P.E. Mullis, E. Peheim and M.G. Bianchetti,199414201206Sheehan, J.P.,199110215219Shils, M.E., J.A. Olson, M. Shils and A. Catharinne Ross,19999th Edn.,Sjogren, A., C.H. Floren and A. Nilsson,198635459463Sjogren, A., C.H. Floren and A. Nilsson,1988224461466Tosiello, L.,199615611431148Walti, M.K., M.B. Zimmermann, G.A. Spinas and R.F. Hurrell,2003133289292Young, D.S.,19903rd Edn.,Zargar, A.H., N.A. Shah, S.R. Massodi, B.A. Laway and F.A. Dar et al.,199874665668Walter, R.M., J.Y. Uriu-Hare, K.L. Olin, M.H. Oster, B.D. Anawalt, J.W. Critchfield and C.L. Keen,19911410501056