Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2005.43.46Lentinus edodes Berk) Extracts]]>DeocarisCuster C. CastroMa. Consolacion P. deOabelAngel T.L. CoElisa MojicaElmer- Rico E.1200551The formation of new blood vessel from pre-existing vessels or angiogenesis is an important phenomenon in the pathology of solid tumor growth and metastasis. We found that chloroform extracts from Lentinus edodes (Berk.) Sing., an edible mushroom reported to demonstrate anti-tumor and immunomodulatory activities inhibited heparin-induced angiogenesis on chick chorioallantoic membrane. Methanol and hexane fractions appeared to have no anti-angiogenic activity. This study holds promise for the potential use of this mushroom as a dietary supplement for the management of various angiogenic-related diseases, especially cancer.]]>Folkman, J.,197128511821186Folkman, J.,197419221258Folkman, J., R. Langer, R.J. Linhardt, C. Haudenschild and S. Taylor,1983221719725Moses, M.A., J. Sudhalter and R. Langer,199024814081410O'Reilly, M.S., L. Holmgren, Y. Shing, C. Chen and R. Rosenthal et al.,199479315328O'Reilly, M.S., T. Boehm, Y. Shing, N. Fukai and G. Vasios et al.,199788277285Olson, K.A., J.W. Fett, T.C. French, M.E. Key and B.L. Vallee,1995in vivo.]]>92442446McCarty, M.F.,199850511514Fotsis, T., M. Pepper, H. Adlercreutz, G. Fleischmann, T. Hase, R. Montesano and L. Schweigerer,1993in vitro angiogenesis.]]>9026902694Shukla, Y., A. Arora and A. Singh,2002154147Sato, K., M. Mochizuki, I. Saiki, Y.C. Yoo, K. Samukawa and I. Azuma,1994Panax ginseng, ginsenoside-Rb2.]]>17635639Davis, P.F., Y. He, R.H. Furneaux, P.S. Johnston, B.M. Ruger and G.C. Slim,199754178182Chihara, G., Y. Maeda, J. Hamuro, T. Sasakia and F. Fukuoka,1969Lentinus edodes (Berk.) sing.]]>222687688Chihara, G., J. Hamuro, Y. Maeda, Y. Arai and F. Fukuoka,1970Lentinus edodes (Berk) Sing. (An edibole mushroom).]]>3027762781Fujii, T., H. Maeda, F. Suzuki and N. Ishida,1978Lentinus edodes.]]>3110791090Sugano, N., Y. Hibino, Y. Choji and H. Maeda,1982Lentinus edodes mycelia.]]>17109114Sugano, N., Y. Choji, Y. Hibino, S. Yasumura and H. Maeda,1985Lentinus edodes mycelia.]]>2716Jiang, S.M., Z.M. Xiao and Z.H. Xu,19995404407Zhang, P. and P.C. Cheung,2002Lentinus edodes α-(/3)-D-glucan as a potential antitumor agent.]]>6610521056Ng, M.L. and A.T. Yap,2002Lentinus edodes).]]>8581589Klauber, N., F. Bowne, B. Anand-Apte and R.J. D`Amato,1996in vitro and in vivo.]]>9425662571Ribatti, D., B. Nico, A. Vacca, L. Roncali and M. Presta,199938995Wood, J., K. Bonjean, S. Ruetz, A. Bellahcene and L. Devy et al.,200230210551061Van der Schaft, D.W.J., R.P.M. Dings, Q.G. de Lussanet, L.I. van Eijk and A.W. Nap et al.,20021619911993Shimamura, M., H. Nagasawa, H. Ashino, Y. Yamamoto and T. Hazato et al.,200388307313Mongiat, M, S.M. Sweeney, J.D. San Antonio, J. Fu and R.V. Iozzo,200327842384249Sia, G.M. and J.K. Candlish,1999Lentinus edodes) extract on human neutrophils and the U937 monocytic cell line.]]>13133137Hatvani, N.,2001Lentinus edodes mycelium grown in submerged liquid culture.]]>177174Hamuro, J. and G. Chihara,1984Chapter 19,pp: 409-436pp: 409-436Aoki, T.,1984pp: 63-77pp: 63-77Riordan, M.H., X. Meng and H.D. Riordan,20002000Daniel, T.,20002000