Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2004.124.127Asad-Ud-DaulaM. KhanamJ.A. RanaA.Y.K.M. Masud 2200442Antibacterial and antifungal activity of 2-oxo benzylidine (3-oxo aniline) Cu (II)-ethylindiamine has been tested against a number of pathogenic bacteria and fungus with different doses. At dose 25 μg disc-1 the compound showed 6-13 mm diameter zone of inhibition against all of the tested bacteria which was found to be larger range as compared to cotrimoxazole (15-29 mm) at the same dose. Minimum inhibitory concentration was withinin the range of 64-128 μg ml-1 against all of the tested bacteria. The compound showed 0-13 mm diameter zone of inhibition against all of the tested fungus at dose 45 μg disc-1 which was found to be larger range as compared with nystatin. The brine shrimp lethality of the compound was found to be 5.23 μg ml-1 which shows a pronounced cytotoxic effect.]]>Saidul Islam, M., M.A. Farooque and M.A.K. Badruddoza,20025335337Khanam, J.A., S.P. Bag, B. Sur and P. Sur,1997Ehrlich ascites carcinoma in mice.]]>29157161Yano, S., S. Inoue, R. Nouchi, K. Mogami and Y. Shinohara et al.,1998Candida albicans.]]>691523Jouad, E.M., G. Larcher, M. Allain, A. Riou, G.M. Bouet, M.A. Khan and X.D. Thanh,200186565571Ibrahim, G., G.M. Bouet, I.H. Hall and M.A. Khan,2000812934Bauer, A.W., W.M.M. Kirby, J.C. Sherris and M. Turck,196645493496Meyer, B.N., N.R. Ferrigni, J.E. Putnam, L.B. Jacobsen, D.E. Nichols and J.L. McLaughlin,1982453134Jawetz, E., J.L. Melnick and E.A. Adelberg,198014th Edn.,pp: 123-124pp: 123-124Attaur, R. and W.J. Thomsen,1999pp: 12-22pp: 12-22