Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2003.289.293IslamM. Saidul HossainMd. Belayet Yeamin RezaMd. 4200334Mixed-ligand transition metal complexes of Co (II) ions were synthesized, where, Maleicacid as a primary ligands and heterocyclic amine bases as a secondary ligands have been used, respectively. Moreover, mixed-ligands transition metal complexes of Fe (III) ions were also synthesized by the same way. Their conventional physical and chemical analysis has been done. Their anti-bacterial and anti-fungal activity has been evaluated. Disc diffusion methods were employed for anti-microbial assays against 14 pathogenic bacteria (5 g positive and 9 g negative) and 14 fungi. The complexes containing 8-hyroxy-quinoline as secondary ligand were much more microbial activity than the other complexes. In addition, the complexes K[Co(II)(ME)(8-HQ)] shows the highest anti bacterial activity against all bacterial tasted (when, ME=C4 H2O4 and 8-HQ=C9H6NO).]]>Baranyi, A. and O. Feher,197947745751Bauer, A.W., W.M.M. Kirby, J.C. Shesies and M. Turck,19664493496Dell, B.O.,19803322232224Islam, M.S.,1986+2 and Ni+2 with diphenicacid as a primary and heterocyclic bases as a secondary ligands synth.]]>16553553Islam, M.S., M.A. Farroque, M.A.K. Bodruddoza, M.A. Mosaddik and M.S. Alam,20002797799Khadikar, P.V., R. Saxena, T. Khaddar and M.A. Feraqui,199456215219Kulieve, A.M., M.A. Shakhgel, M.A. Gadzheira and I.A. Aliev,19791979Mayer, J., M. Rohn and P. Mycosen,198023320320Nakazawa, S. and T. Yamauchi,19801980Paajnar, L., K. Kaskela and P. Viitaniemi,19998367575Part, W.B. and W. Ruddon,19891st Edn.,pp: 251-254pp: 251-254Sangal, S.K. and K. Herjinider,199471621623Szente, M., O. Feher and T. Gyuris,198463197197Zakaria, C.M., A. Farroque, M.R. Islam and M.H. Biswas,2000168590