Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2001.368.371Streptomyces
Species]]>AnisuzzamanA. S. M. SugimotoNaoki BhuiyanM. S. A. SadikGolam GafurM. A. 6200116The chloroform extract and the two novel compounds streptmysone-A (I) and streptomysone-B
(II) of the Czapek-Dox (alkaline) culture filtrate of the Streptomyces
species were studied for cytotoxic and acute toxicity activities. The cytotoxic
activity of the compounds and the extract was determined by brine shrimp lethality
bioassay while the acute toxicity study was performed on Swiss albino mice.
The LC50 values of chloroform extract(CHCl3), compound
(I) and (II), and standard ampicillin trihydrate were found to be 3.89, 6.31,
125.8 and 6.31Fg ml-1, respectively. The LD50 values were
found to be 66.34 and 79.49mg kg-1 for the compound (1) and (II),
respectively.]]>Anisurzaman, A.S.M.,2000Aspergillus fumigatus and Streptomyces sp.]]>2000Egon, S.,19692nd Edn.,Goodman, L.S., A.G. Gilmann and A. Gilmann,19806th Edn.,pp: 1299-1313pp: 1299-1313Goldstein, A.L., L. Aronow and S.M. Kalkan,19742nd Edn.,pp: 376-381pp: 376-381Holt, J.G., N.R. Kreig, P.H.A. Sneath, J.T. Staley and S.T. Williams,19949th Edn.,Pages: 787Pages: 787Hammond, S.M. and P.A. Lambert,1978pp: 4-9pp: 4-9Meyer, B.N., N.R. Ferrigni, J.E. Putnam, L.B. Jacobsen, D.E. Nichols and J.L. Mclaughlin,1982453134McLaughlin, J.L. and J.E. Anderson,1988McLaughlin, J.L.,199034114Anisuzzaman, A.S.M., A.T.M.Z. Azam, M.H.U. Biswas and M.A. Gafur,2000Aspergillus fumigatus.]]>1123126Geornaras, I., J.W. Hastings and A. von Holy,2001Escherichia coli strains from poultry carcasses and their susceptibilities to antimicrobial agents.]]>6719401944