Journal of Medical Sciences1682-44741812-5727Asian Network for Scientific Information10.3923/jms.2001.339.342KhanamJ. A. RoyS. Masud RanaA. Y. K. M. 5200115Antitumor activity of sodium salt of cyanohydroxamic acid (CNHA) has been evaluated against Ehrlich ascites carcinoma (EAC) in mice. CNHA inhibited the growth of EAC cells and enhance the longitivity of tumor bearing mice significantly. Hematological parameters and alkaline phosphatase (ALP) activity in tumor bearing mice are found to be significantly altered but CNHA treatment recovered those parameters towards normal values. High mortality rate of brine shrimp nouplii was obtained with CNHA exhibiting pronounced cytotoxic effect.]]>Attaur, R. and W.J. Thomsen,1999pp: 12-22pp: 12-22Bruce, P. and B.J. Kennedy,197011 63 63Coutinho, L.H., M.L. Brereton, A.M.W. Santos, W.D.J. Ryder and T. Chang et al.,199693869877Donehower, R.C.,19901990pp: 225-233pp: 225-233Elford, H.L., G.L. Wampler and B. van't Riet,197939844851Gora-Tybor, J. and T. Robak,1995263945, (In Polish)Ghosh, M.N.,19841st Edn.,pp: 153-157pp: 153-157Jones, L.W. and L.F. Werner,191739413422Khanam, J.A., S.P. Bag, B. Sur and P. Sur,199729157161Litchfield, Jr. J.T. and F. Wilcoxon,19499699113Meyer, B.N., N.R. Ferrigni, J.E. Putnam, L.B. Jacobsen, D.E. Nichols and J.L. McLaughlin,1982453134Moore, E.C.,196929291295Michell, R.H., M.J. Karnovsky and M.L. Karnovsky,1970116207216Nand, S., W. Stock, J. Godwin and S.G. Fisher, 1996524246Rusia, U. and K.S. Swarup,19881988pp: 228-257pp: 228-257Santarossa, S., E. Vaccher, O. Lenardon, A. Merlo, D. Errante and U. Tirelli,19953117181718Sur, P. and D.K. Ganguly,199460106109Sur, P., S.P. Bug, B. Sur and J.A. Khanam,1997Ehrlich ascites carcinoma in mice.]]>44197201Sur, P., B. Hazra, D.K. Roy, B. Sur, D.K. Roy and B. Sur,198422115119Young, C.W., G. Schochetman, S. Hodas and M.E. Balis,196727535540