Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2013.63.69Trichodesma indicum and Trichodesma sedgwickianum]]>SabooS.S. TapadiyaG.G. KhadabadiS.S. 1201381Traditionally important plant Trichodesma sedgwickianum and Trichodesma indicum has therapeutic utility in folk medicine having anti-inflammatory, wound healing and anticancer properties; this led us to carry out the a research based study on antimicrobial properties and identification of phytoconstituents. The antimicrobial activity has been checked against five gram positive and gram negative bacteria and three fungi. The zone of inhibition of extracts ranged from 12 to 29 mm. The MIC was found in the range of 5 to 0.625 mg mL-1. Amongst the extracts, ethanol extract of both species was more active against gram positive bacteria, S. aureus and B. subtilis whereas aqueous extract had having strong inhibitory effect against gram negative bacteria like E. coli and other organism. Phytochemically they contain steroidal, b-sitosterol and phenolics, catechin and gallic acid (HPLC). Plants have proved to be significant natural resources as effective antimicrobial and chemotherapeutic agents and offer a broad spectrum of activity with greater emphasis on preventive action.]]>Arora, D.S. and J. Kaur,199912257262Chanwitheesuk, A., A. Teerawutgulrag, J.D. Kilburn and N. Rakariyatham,2007Caesalpinia mimosoides Lamk.,]]>10010441048Duru, C.M. and N.E. Onyedineke,2010In vitro study on the antimicrobial activity and phytochemical analysis of ethanolic extracts of the mesocarp of Voacanga africana.]]>5163169Hancock, R.E.W.,20055209218Khandelwal, K.R.,201020th Edn.,Kirtikar, K.R. and B.D. Basu, 19351st Edn.,NCCLS,19971997NCCLS,19971997Prasad, R.N., S. Viswanathan, J.R. Devi, V. Nayak and V.C. Swetha et al.,2008Samanea saman.]]>2268270Oladunmoye, M.K., F.C. Adetuyi and F.A. Akinyosoye,2007Cassia hirsuta (L.) extract on DNA profile of some microorganisms.]]>2142146Pereira, J.A., A.P.G. Pereira, I.C.F.R. Ferreira, P. Valentao and P.B. Andrade et al.,20065484258431Rauha, J.P., S. Remes, M. Heinonen, A. Hopia and M. Kahkonen et al.,200056312Skoog, D.A., F.J. Holler and T.A. Nieman,19985th Edn.,pp: 13-14pp: 13-14Sofowora, A.,1982Vol. 131,pp: 168-171pp: 168-171Taylor, P.W., J.M.T. Hamilton-Miller and P.D. Stapleton,200527181Malik, T. and P. Singh,201039298